Caficrestat
Caficrestat is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Events
FDA approval date
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Study first post date
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Commercial
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Clinical
Clinical Trials
150 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | — | 1 | — | — | — | 1 |
| Head and neck neoplasms | D006258 | — | — | — | 1 | — | — | — | 1 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | — | 1 | — | — | — | 1 |
| Squamous cell carcinoma | D002294 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Caficrestat |
| INN | caficrestat |
| Description | Caficrestat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | enzyme inhibitors: aldose-reductase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c(=O)c2nccnc12 |
Identifiers
| PDB | — |
| CAS-ID | 1355612-71-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297455 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | E8I3O45DDU (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 754 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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