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Drug ReportsCARFENTANIL
CARFENTANIL
Carfentanil is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target delta-type opioid receptor, kappa-type opioid receptor, and mu-type opioid receptor.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeuralgiaD009437EFO_0009430——1——12
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ObesityD009765EFO_0001073E66.91———23
Opioid-related disordersD009293EFO_0005611F112————2
Substance-related disordersD019966EFO_0003890F131————1
Healthy volunteers/patients———1————1
AlcoholismD000437EFO_0003829F10.11————1
Alcohol drinkingD000428EFO_0004329—1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Addictive behaviorD016739EFO_0004347—————11
Trigeminal neuralgiaD014277EFO_1001219G50.0————11
Parkinson diseaseD010300EFO_0002508G20————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCARFENTANIL
INNcarfentanil
Description
Carfentanil is a monocarboxylic acid amide resulting from the formal condensation of the aryl amino group of methyl 4-anilino-1-(2-phenylethyl)piperidine-4-carboxylate with propanoic acid. It has a role as a mu-opioid receptor agonist, an opioid analgesic and a tranquilizing drug. It is a member of piperidines, a methyl ester, a tertiary amino compound and a tertiary carboxamide.
Classification
Small molecule
Drug classnarcotic analgesics (fentanyl derivatives)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCc2ccccc2)CC1
Identifiers
PDB—
CAS-ID59708-52-0
RxCUI—
ChEMBL IDCHEMBL290429
ChEBI ID61084
PubChem CID62156
DrugBankDB01535
UNII IDLA9DTA2L8F (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
OPRD1
OPRD1
OPRK1
OPRK1
OPRM1
OPRM1
Organism
Homo sapiens
Gene name
OPRD1
Gene synonyms
OPRD
NCBI Gene ID
Protein name
delta-type opioid receptor
Protein synonyms
D-OR-1, delta opioid receptor 1, DOR-1
Uniprot ID
Mouse ortholog
Oprd1 (18386)
delta-type opioid receptor (P32300)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 2,011 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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200 adverse events reported
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