Bromhexine
Bromhexine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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12 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Respiratory tract diseases | D012140 | — | — | — | — | 1 | — | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Bromhexine |
| INN | bromhexine |
| Description | Bromhexine is a substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum). It has a role as a mucolytic. It is a substituted aniline, a tertiary amino compound and an organobromine compound. It is a conjugate base of a bromhexine(1+). |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1 |
Identifiers
| PDB | — |
| CAS-ID | 3572-43-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL253376 |
| ChEBI ID | 77032 |
| PubChem CID | 2442 |
| DrugBank | DB09019 |
| UNII ID | Q1J152VB1P (ChemIDplus, GSRS) |
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Safety
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365 adverse events reported
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