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Drug ReportsBromhexine
Bromhexine
Bromhexine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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COVID-19
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
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Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
R: Respiratory system drugs
R05: Cough and cold preparations
R05C: Expectorants, excl. combinations with cough suppressants
R05CB: Mucolytics
R05CB02: Bromhexine
HCPCS
No data
Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Covid-19D0000863821236
PneumoniaD011014EFO_0003106112
InfectionsD007239EFO_000054411
Communicable diseasesD00314111
BronchiolitisD001988HP_001195011
Treatment outcomeD01689611
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Coronavirus infectionsD018352EFO_0007224B34.2112
Respiratory tract diseasesD01214011
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
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Total
PharmacokineticsD01059911
Healthy volunteers/patients11
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Sars-cov-2D00008640211
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBromhexine
INNbromhexine
Description
Bromhexine is a substituted aniline that is 2,4-dibromoaniline which is substituted at position 6 by a [cyclohexyl(methyl)amino]methyl group. It is used (as the monohydrochloride salt) as a mucolytic for the treatment of respiratory disorders associated with productive cough (i.e. a cough characterised by the production of sputum). It has a role as a mucolytic. It is a substituted aniline, a tertiary amino compound and an organobromine compound. It is a conjugate base of a bromhexine(1+).
Classification
Small molecule
Drug class
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Structure (InChI/SMILES or Protein Sequence)
CN(Cc1cc(Br)cc(Br)c1N)C1CCCCC1
Identifiers
PDB
CAS-ID3572-43-8
RxCUI
ChEMBL IDCHEMBL253376
ChEBI ID77032
PubChem CID2442
DrugBankDB09019
UNII IDQ1J152VB1P (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,005 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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365 adverse events reported
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