Bleomycin
Bleomycin (bleomycin) is a small molecule pharmaceutical. Bleomycin was first approved as Blenoxane on 1982-01-01. It is used to treat choriocarcinoma, hodgkin disease, melanoma, non-hodgkin lymphoma, and sarcoma amongst others in the USA.
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Commercial
Trade Name
FDA
EMA
Bleomycin (discontinued: Blenoxane, Bleomycin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Bleomycin sulfate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| BLENOXANE | Bristol Myers Squibb | N-050443 DISCN | 1982-01-01 | 2 products, RLD |
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FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| bleomycin | ANDA | 2024-10-10 |
Indications
FDA
EMA
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J9040 | Injection, bleomycin sulfate, 15 units |
Clinical
No data
Drug
General
| Drug common name | Bleomycin |
| INN | bleomycin |
| Description | Bleomycin A2 is a bleomycin. It has a role as an antineoplastic agent and a metabolite. |
| Classification | Small molecule |
| Drug class | antibiotics (Streptomyces strain) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1c(N)nc([C@H](CC(N)=O)NC[C@H](N)C(N)=O)nc1C(=O)N[C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@H](C(=O)NCCc1nc(-c2nc(C(=O)NCCC[S+](C)C)cs2)cs1)[C@@H](C)O)[C@@H](O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)c1c[nH]cn1 |
Identifiers
| PDB | — |
| CAS-ID | 11056-06-7 |
| RxCUI | 1622 |
| ChEMBL ID | CHEMBL403664 |
| ChEBI ID | 3139 |
| PubChem CID | 5460769 |
| DrugBank | DB00290 |
| UNII ID | 40S1VHN69B (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
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Trends
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Safety
Black-box Warning
Black-box warning for: Bleomycin
Adverse Events
0 adverse events reported
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