Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Macular degeneration | D008268 | EFO_0001365 | H35.30 | 1 | 1 | 2 | — | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Macular edema | D008269 | — | — | — | 1 | — | — | — | 1 |
Edema | D004487 | HP_0000969 | R60.9 | — | 1 | — | — | — | 1 |
Drug common name | Bevasiranib |
INN | bevasiranib |
Description | Bevasiranib is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies. |
Classification | Oligonucleotide |
Drug class | angiogenesis inhibitors; small interfering RNA (siRNA) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)O[C@H]3C[C@H](n4cc(C)c(=O)[nH]c4=O)O[C@@H]3COP(=O)(O)O[C@@H]3[C@@H](COP(=O)(O)O[C@@H]4[C@@H](COP(=O)(O)O[C@@H]5[C@@H](COP(=O)(O)O[C@@H]6[C@@H](COP(=O)(O)O[C@@H]7[C@@H](COP(=O)(O)O[C@@H]8[C@@H](COP(=O)(O)O[C@@H]9[C@@H](COP(=O)(O)O[C@@H]%10[C@@H](COP(=O)(O)O[C@@H]%11[C@@H](COP(=O)(O)O[C@@H]%12[C@@H](COP(=O)(O)O[C@@H]%13[C@@H](COP(=O)(O)O[C@@H]%14[C@@H](COP(=O)(O)O[C@@H]%15[C@@H](COP(=O)(O)O[C@@H]%16[C@@H](COP(=O)(O)O[C@@H]%17[C@@H](COP(=O)(O)O[C@@H]%18[C@@H](COP(=O)(O)O[C@@H]%19[C@@H](COP(=O)(O)O[C@@H]%20[C@@H](COP(=O)(O)O[C@@H]%21[C@@H](CO)O[C@@H](n%22cnc%23c(N)ncnc%23%22)[C@@H]%21O)O[C@@H](n%21ccc(N)nc%21=O)[C@@H]%20O)O[C@@H](n%20ccc(N)nc%20=O)[C@@H]%19O)O[C@@H](n%19ccc(=O)[nH]c%19=O)[C@@H]%18O)O[C@@H](n%18ccc(N)nc%18=O)[C@@H]%17O)O[C@@H](n%17cnc%18c(N)ncnc%18%17)[C@@H]%16O)O[C@@H](n%16ccc(N)nc%16=O)[C@@H]%15O)O[C@@H](n%15ccc(N)nc%15=O)[C@@H]%14O)O[C@@H](n%14cnc%15c(N)ncnc%15%14)[C@@H]%13O)O[C@@H](n%13cnc%14c(N)ncnc%14%13)[C@@H]%12O)O[C@@H](n%12cnc%13c(=O)[nH]c(N)nc%13%12)[C@@H]%11O)O[C@@H](n%11cnc%12c(=O)[nH]c(N)nc%12%11)[C@@H]%10O)O[C@@H](n%10ccc(N)nc%10=O)[C@@H]9O)O[C@@H](n9ccc(N)nc9=O)[C@@H]8O)O[C@@H](n8cnc9c(N)ncnc98)[C@@H]7O)O[C@@H](n7cnc8c(=O)[nH]c(N)nc87)[C@@H]6O)O[C@@H](n6ccc(N)nc6=O)[C@@H]5O)O[C@@H](n5cnc6c(N)ncnc65)[C@@H]4O)O[C@@H](n4ccc(N)nc4=O)[C@@H]3O)O2)c(=O)[nH]c1=O |
PDB | — |
CAS-ID | 959961-96-7 |
RxCUI | — |
ChEMBL ID | CHEMBL2110581 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | DGN36694W4 (ChemIDplus, GSRS) |