Bepridil
Bepadin, Vascor (bepridil) is a small molecule pharmaceutical. Bepridil was first approved as Vascor on 1990-12-28. It is used to treat angina pectoris and hypertension in the USA. It is known to target potassium channel subfamily T member 1 and potassium voltage-gated channel subfamily KQT member 4.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| cardiovascular diseases | D002318 |
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Bepridil hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| VASCOR | Johnson & Johnson | N-019002 DISCN | 1990-12-28 | 3 products |
| BEPADIN | Medpointe Pharm Hlc | N-019001 DISCN | 1990-12-28 | 3 products |
Hide discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| hypertension | EFO_0000537 | D006973 | I10 |
| angina pectoris | EFO_0003913 | D000787 | I20 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
| Marfan syndrome | D008382 | Orphanet_558 | Q87.4 | — | — | — | — | 1 | 1 |
| Bicuspid aortic valve disease | D000082882 | — | — | — | — | — | — | 1 | 1 |
| Aortic aneurysm | D001014 | EFO_0001666 | I71.9 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Bepridil |
| INN | bepridil |
| Description | Bepridil is a tertiary amine in which the substituents on nitrogen are benzyl, phenyl and 3-(2-methylpropoxy)-2-(pyrrolidin-1-yl)propyl. It has a role as a vasodilator agent, an anti-arrhythmia drug, an antihypertensive agent and a calcium channel blocker. It is a tertiary amine and a member of pyrrolidines. |
| Classification | Small molecule |
| Drug class | vasodilators (undefined group) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)COCC(CN(Cc1ccccc1)c1ccccc1)N1CCCC1 |
Identifiers
| PDB | — |
| CAS-ID | 64706-54-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1008 |
| ChEBI ID | 3061 |
| PubChem CID | 2351 |
| DrugBank | DB01244 |
| UNII ID | 755BO701MA (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
NOTUM
NOTUM
Organism
Homo sapiens
Gene name
NOTUM
Gene synonyms
NCBI Gene ID
Protein name
palmitoleoyl-protein carboxylesterase NOTUM
Protein synonyms
[Wnt protein] O-palmitoleoyl-L-serine hydrolase, hNOTUM, notum pectinacetylesterase homolog, protein notum homolog
Uniprot ID
Mouse ortholog
Notum (77583)
palmitoleoyl-protein carboxylesterase NOTUM (Q8R116)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 1,459 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
166 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use