Bepirovirsen
Bepirovirsen is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hepatitis b | D006509 | — | — | 5 | 9 | 2 | — | — | 15 |
| Hepatitis | D006505 | — | K75.9 | 4 | 8 | 2 | — | — | 13 |
| Chronic hepatitis b | D019694 | EFO_0004239 | B18.1 | 1 | 8 | 2 | — | — | 10 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | 1 | 7 | 2 | — | — | 9 |
| Chronic hepatitis | D006521 | — | K73.9 | 1 | 5 | 2 | — | — | 7 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Herpesviridae infections | D006566 | EFO_0007309 | B00.4 | — | 2 | — | — | — | 2 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | — | 1 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | — | 1 | — | — | — | 1 |
| Virus diseases | D014777 | — | B34 | — | 1 | — | — | — | 1 |
| Immunologic deficiency syndromes | D007153 | — | D84.9 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | — | — | — | — | 1 |
| Renal insufficiency | D051437 | — | N19 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Bepirovirsen |
| INN | bepirovirsen |
| Description | Bepirovirsen (GSK3228836) is an antisense oligonucleotide developed to treat hepatitis B infection.
|
| Classification | Oligonucleotide |
| Drug class | antisense oligonucleotides: antivirals; antivirals |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4650468 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | Z87O6SM01N (ChemIDplus, GSRS) |
Target
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Variants
No data
Financial
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Bepirovirsen – Ionis Pharmaceuticals
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Tabular view
Estimated US medical usage
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 188 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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