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Drug ReportsBenzthiazide
Benzthiazide
Aquatag, Exna, Fovane, Urese (benzthiazide) is a small molecule pharmaceutical. Benzthiazide was first approved as Exna on 1982-01-01. It is used to treat edema, heart failure, hypertension, and nephrotic syndrome in the USA.
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MeSH
urogenital diseasesD000091642
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
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Abbreviated New Drug Application (ANDA)
Benzthiazide
Tradename
Company
Number
Date
Products
EXNAA.H. Robins CompanyN-012489 DISCN1982-01-01
1 products
FOVANEPfizerN-012128 DISCN1982-01-01
1 products
URESEPfizerN-012128 DISCN1982-01-01
1 products
AQUATAGSolvay PharmaceuticalsN-016001 DISCN1982-01-01
2 products
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General
Drug common nameBenzthiazide
INNbenzthiazide
Description
Benzthiazide is 7-Sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide in which the hydrogen at position 6 is substituted by chlorine and that at position 3 is substituted by a benzylsulfanylmethyl group. A diuretic, it is used to treat hypertension and edema. It has a role as a diuretic and an antihypertensive agent. It is a benzothiadiazine and a sulfonamide.
Classification
Small molecule
Drug classdiuretics (thiazide derivatives)
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Structure (InChI/SMILES or Protein Sequence)
NS(=O)(=O)c1cc2c(cc1Cl)N=C(CSCc1ccccc1)NS2(=O)=O
Identifiers
PDB
CAS-ID91-33-8
RxCUI
ChEMBL IDCHEMBL1201039
ChEBI ID3047
PubChem CID2343
DrugBankDB00562
UNII ID1TD8J48L61 (ChemIDplus, GSRS)
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Safety
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19 adverse events reported
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