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Drug ReportsBeclomethasone
Beclovent, Trimbow(beclomethasone dipropionate)
Beconase, CHF 5993 Chiesi Farmaceutici S.p.A, Qnasl, Qvar, Riarify, Trimbow, Trydonis, Vancenase (beclomethasone dipropionate) is a small molecule pharmaceutical. Beclomethasone dipropionate was first approved as Beclovent on 1982-01-01. It is used to treat allergic rhinitis perennial and inflammation in the USA. It has been approved in Europe to treat chronic obstructive pulmonary disease. It is known to target adhesion G protein-coupled receptor G3.
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Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
immune system diseasesD007154
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Qnasl, Qvar (discontinued: Beclovent, Beconase, Qvar, Vancenase, Vanceril)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Beclomethasone dipropionate
Tradename
Company
Number
Date
Products
QVAR REDIHALERNorton WaterfordN-207921 RX2017-08-03
2 products, RLD
QNASLTevaN-202813 RX2012-03-23
2 products, RLD, RS
Show 7 discontinued
Beclomethasone dipropionate monohydrate
Tradename
Company
Number
Date
Products
BECONASE AQGSKN-019389 DISCN1987-07-27
1 products, RLD
VANCENASE AQMerck & CoN-019589 DISCN1987-12-23
1 products
VANCENASE AQMerck & CoN-020469 DISCN1996-06-26
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
5 in 1 clipper spryOTC monograph not final2020-10-16
beconaseNew Drug Application2010-09-08
beconase aqNew Drug Application2009-10-27
qnaslNew Drug Application2022-09-27
qvarNew Drug Application2018-08-31
qvar redihalerNew Drug Application2025-08-20
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
inflammationMP_0001845D007249—
allergic rhinitis perennialEFO_1001417D012221J30.89
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Beclomethasone Dipropionate, Qvar Redihaler, Norton Waterford
115836432041-08-19DP
115596372039-07-21DP
107924472039-01-25DP
113958882038-01-26DP
117939532038-01-26DP
118652472038-01-26DP
89314762031-07-17DP
81327122028-09-07DP
Beclomethasone Dipropionate, Qvar 40, Teva Branded Pharm
105618082032-01-01DP
94632892031-05-18DP
98085872031-05-18DP
100225092031-05-18DP
100225102031-05-18DP
100861562031-05-18DP
106955122031-05-18DP
113958892031-05-18DP
Beclomethasone Dipropionate, Qnasl, Teva Branded Pharm
101888112031-10-21DP
77800382027-01-24DP
ATC Codes
A: Alimentary tract and metabolism drugs
— A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
— A07E: Intestinal antiinflammatory agents
— A07EA: Corticosteroids acting locally
— A07EA07: Beclometasone
D: Dermatologicals
— D07: Corticosteroids, dermatological preparations
— D07A: Corticosteroid dermatological preparations, plain
— D07AC: Corticosteroids, potent (group iii)
— D07AC15: Beclometasone
— D07C: Corticosteroids, combinations with antibiotics
— D07CC: Corticosteroids, potent, combinations with antibiotics
— D07CC04: Beclometasone and antibiotics
R: Respiratory system drugs
— R01: Nasal preparations
— R01A: Decongestants and other nasal preparations for topical use
— R01AD: Corticosteroid nasal preparations for topical use
— R01AD01: Beclometasone
— R03: Drugs for obstructive airway diseases
— R03A: Adrenergics, inhalants
— R03AK: Adrenergics inhalants in combination with corticosteroids or other drugs, excl. anticholinergics
— R03AK08: Formoterol and beclometasone
— R03AK13: Salbutamol and beclometasone
— R03AL: Adrenergics in combination with anticholinergics incl. triple combinations with corticosteroids
— R03AL09: Formoterol, glycopyrronium bromide and beclometasone
— R03B: Other drugs for obstructive airway diseases, inhalants in atc
— R03BA: Glucocorticoid inhalants for obstructive airway disease
— R03BA01: Beclometasone
HCPCS
No data
Clinical
Clinical Trials
251 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J45—184821
Lung diseasesD008171EFO_0003818J98.4———112
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Allergic rhinitisD065631—J30.9115—18
RhinitisD012220EFO_0008521J31115—18
Allergic rhinitis perennialD012221EFO_1001417J30.89——4—15
Allergic rhinitis seasonalD006255EFO_0003956J30—12——3
HypersensitivityD006967EFO_0003785T78.40——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bronchial hyperreactivityD016535———1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PharmacokineticsD010599——1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SmokingD012907EFO_0004318—————11
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.9————11
Obstructive lung diseasesD008173——————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBeclomethasone dipropionate
INNbeclometasone
Description
Beclomethasone dipropionate is a steroid ester comprising beclomethasone having propionyl groups at the 17- and 21-positions. It has a role as an anti-inflammatory drug, an anti-asthmatic drug, a prodrug and an anti-arrhythmia drug. It is a steroid ester, an enone, a 20-oxo steroid, an 11beta-hydroxy steroid, a propanoate ester, a corticosteroid, a glucocorticoid, a 3-oxo-Delta(1),Delta(4)-steroid and a chlorinated steroid. It is functionally related to a beclomethasone.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(Cl)[C@@H](O)C[C@@]21C
Identifiers
PDB—
CAS-ID5534-09-8
RxCUI—
ChEMBL IDCHEMBL1200500
ChEBI ID3002
PubChem CID21700
DrugBankDB00394
UNII IDKGZ1SLC28Z (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
ADGRG3
ADGRG3
Organism
Homo sapiens
Gene name
ADGRG3
Gene synonyms
GPR97, PGR26
NCBI Gene ID
222487
Protein name
adhesion G protein-coupled receptor G3
Protein synonyms
G protein-coupled receptor 97, G-protein coupled receptor 97, G-protein coupled receptor PGR26, probable G-protein coupled receptor 97
Uniprot ID
Q8IZF1
Mouse ortholog
Adgrg3 (54672)
adhesion G protein-coupled receptor G3 (Q8R0T6)
Variants
No data
Financial
Revenue by drug
$
€
£
₣
Qvar – Teva
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Estimated US medical usage
Beclomethasone dipropionate
+
Beclomethasone
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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8,783 adverse events reported
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