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Drug ReportsBacitracin
Bacitracin
Bacitracin, Bacitracin / / Neomycin / Polymyxin B, Bacitracin / Neomycin / Polymyxin B, Bacitracin / Polymyxin B, Lumi-sporyn, Mycitracin (bacitracin) is a protein pharmaceutical. Bacitracin was first approved as Bacitracin on 1982-01-01. It is used to treat bacterial eye infections, bacterial skin diseases, empyema, pneumonia, and pseudomembranous enterocolitis amongst others in the USA.
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Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
digestive system diseasesD004066
respiratory tract diseasesD012140
eye diseasesD005128
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Bacitracin (discontinued: Baciguent, Bacitracin)
Combinations
Bacitracin polymyxin b, Bacitracin-neomycin-polymyxin w/ hydrocortisone, Lumi-sporyn, Neomycin polymyxin b sulfates bacitracin, Neomycin polymyxin b sulfates, bacitracin hydrocortisone (discontinued: Bacitracin polymyxin b, Bacitracin-neomycin-polymyxin, Bacitracin-neomycin-polymyxin w/ hydrocortisone, Cortisporin, Lanabiotic, Mycitracin, Neo-polycin, Neomycin polymyxin b sulfates bacitracin, Neomycin polymyxin b sulfates, bacitracin hydrocortisone, Polysporin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Bacitracin zinc
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
POLYSPORINGSKN-050167 DISCN1985-03-01
1 products
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Bacitracin zinc
+
Hydrocortisone
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
CORTISPORINCasper PharmaN-050416 DISCN1982-01-01
1 products, RLD
CORTISPORINMonarch PharmaceuticalsN-050168 DISCN1984-05-04
1 products, RLD
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Bacitracin
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
LANABIOTICCombeN-050598 DISCN1986-09-22
1 products
Hide discontinued
Bacitracin zinc
+
Neomycin sulfate
+
Polymyxin b sulfate
Tradename
Company
Number
Date
Products
LUMI-SPORYNCasper PharmaN-050417 RX1982-01-01
1 products, RLD
Labels
FDA
EMA
Brand Name
Status
Last Update
0.9g triple antibioticOTC monograph final2022-03-24
10 person ansiOTC monograph final2010-06-07
25 person ansiOTC monograph final2010-06-07
4314 first aid kit 4315 first aid kitunapproved drug other2019-05-10
50 person ansiOTC monograph final2010-06-07
acme first aid contains 404 piecesOTC monograph final2010-06-07
acme small cuts and burnsOTC monograph final2010-06-14
advanced first aid bacitracinOTC monograph final2016-10-18
adventure first aid .5 tinOTC monograph not final2017-03-16
adventure medical kits 1-2 person first aidOTC monograph not final2011-01-11
Show 339 more
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
D06: Antibiotics and chemotherapeutics for dermatological use
D06A: Antibiotics for topical use
D06AX: Other antibiotics for topical use in atc
D06AX05: Bacitracin
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01X: Other antibacterials in atc
J01XX: Other antibacterials in atc
J01XX10: Bacitracin
R: Respiratory system drugs
R02: Throat preparations
R02A: Throat preparations
R02AB: Antibiotic throat preparations
R02AB04: Bacitracin
HCPCS
No data
Clinical
No data
Drug
General
Drug common nameBacitracin
INNbacitracin
Description
Bacitracin is a mixture of related cyclic peptides produced by organisms of the licheniformis group of Bacillus subtilis var Tracy, first isolated in 1945. These peptides disrupt Gram-positive bacteria by interfering with cell wall and peptidoglycan synthesis.
Classification
Protein
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC[C@H](C)[C@H](N)C1=N[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](C(=O)N[C@H]2CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(=O)O)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC)CS1
Identifiers
PDB
CAS-ID22601-59-8
RxCUI
ChEMBL IDCHEMBL1200558
ChEBI ID35862
PubChem CID439542
DrugBankDB00626
UNII ID58H6RWO52I (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
No data
Estimated US medical usage
Bacitracin
Total medical expenditures per year (USD, in millions)
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Bacitracin
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Neomycin
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Polymyxin b
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Bacitracin
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Polymyxin b
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Bacitracin
+
Polymyxin b
+
Pramoxine
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Tabular view
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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