BARUSIBAN
Barusiban is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infertility | D007246 | HP_0000789 | — | — | 1 | — | — | — | 1 |
| Premature obstetric labor | D007752 | — | O60 | — | 1 | — | — | — | 1 |
| Premature birth | D047928 | EFO_0003917 | O60 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | BARUSIBAN |
| INN | barusiban |
| Description | Barusiban (INN) (code name FE-200440) is a non-peptide drug which is among the most potent and selective oxytocin receptor antagonists known. It was trialed by Ferring Pharmaceuticals as a treatment of preterm labor but failed to demonstrate effectiveness and was not pursued any further.
|
| Classification | Protein |
| Drug class | oxytocin antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC[C@H](C)[C@@H]1NC(=O)[C@@H](Cc2c[nH]c3ccccc23)NC(=O)CCSCC[C@@H](C(=O)N(C)[C@H](CO)CCCN)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H]([C@H](C)CC)NC1=O |
Identifiers
| PDB | — |
| CAS-ID | 285571-64-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2218898 |
| ChEBI ID | — |
| PubChem CID | 9832431 |
| DrugBank | — |
| UNII ID | UX33I93GLS (ChemIDplus, GSRS) |
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Safety
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Adverse Events
0 adverse events reported
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