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Drug ReportsAztreonam
Azactam, Cayston(aztreonam)
Azactam, Aztreonam, Cayston, Emblaveo (aztreonam) is a small molecule pharmaceutical. Aztreonam was first approved as Azactam on 1986-12-31. It is used to treat bacterial infections, cellulitis, endometritis, intraabdominal infections, and pseudomonas infections amongst others in the USA. It has been approved in Europe to treat cystic fibrosis and respiratory tract infections.
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YTD
1Y
2Y
5Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
digestive system diseasesD004066
respiratory tract diseasesD012140
urogenital diseasesD000091642
hereditary congenital and neonatal diseases and abnormalitiesD009358
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Azactam, Aztreonam, Cayston (discontinued: Azactam, Aztreonam)
Combinations
Emblaveo
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Aztreonam
Tradename
Company
Number
Date
Products
AZACTAMBristol Myers SquibbN-050580 RX1986-12-31
2 products, RLD, RS
CAYSTONGilead SciencesN-050814 RX2010-02-22
1 products, RLD, RS
Show 2 discontinued
Avibactam sodium
+
Aztreonam
Tradename
Company
Number
Date
Products
EMBLAVEOAbbVieN-217906 RX2025-02-07
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
azactamNew Drug Application2025-01-09
aztreonamANDA2024-06-03
caystonNew Drug Application2025-03-17
emblaveoNew Drug Application2025-02-07
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01D: Other beta-lactam antibacterials in atc
J01DF: Monobactams
J01DF01: Aztreonam
HCPCS
Code
Description
S0073
Injection, aztreonam, 500 mg
Clinical
Clinical Trials
69 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InfectionsD007239EFO_000054411
Communicable diseasesD00314111
Bacterial infectionsD001424A4911
Gram-negative bacterial infectionsD01690511
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameAztreonam
INNaztreonam
Description
Aztreonam, sold under the brand name Azactam among others, is an antibiotic used primarily to treat infections caused by gram-negative bacteria such as Pseudomonas aeruginosa. This may include bone infections, endometritis, intra abdominal infections, pneumonia, urinary tract infections, and sepsis. It is given by intravenous or intramuscular injection or by inhalation.
Classification
Small molecule
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
C[C@H]1[C@H](NC(=O)/C(=N\OC(C)(C)C(=O)O)c2csc(N)n2)C(=O)N1S(=O)(=O)O
Identifiers
PDB
CAS-ID78110-38-0
RxCUI
ChEMBL IDCHEMBL158
ChEBI ID161680
PubChem CID5742832
DrugBankDB00355
UNII IDG2B4VE5GH8 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
Azactam Elan Corporation
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Tabular view
Estimated US medical usage
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 16,894 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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13,310 adverse events reported
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