Tradename | Company | Number | Date | Products |
---|---|---|---|---|
IMURAN | Sebela Pharmaceuticals | N-016324 RX | 1982-01-01 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
IMURAN | Casper Pharma | N-017391 DISCN | 1982-01-01 | 1 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
azasan | ANDA | 2023-12-18 |
azathioprine | ANDA | 2024-02-08 |
azathioprine sodium | ANDA | 2023-05-15 |
imuran | New Drug Application | 2019-03-20 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Crohn disease | D003424 | EFO_0000384 | K50 | — | 3 | 13 | 12 | 20 | 48 |
Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | 1 | 3 | 6 | 13 | 23 |
Lupus nephritis | D008181 | EFO_0005761 | — | 1 | 6 | 8 | 2 | 3 | 19 |
Inflammatory bowel diseases | D015212 | EFO_0003767 | — | 1 | — | — | 4 | 14 | 19 |
Systemic lupus erythematosus | D008180 | HP_0002725 | M32 | 3 | 7 | 6 | 1 | 1 | 16 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | 6 | 2 | 2 | 10 |
Granulomatosis with polyangiitis | D014890 | EFO_0005297 | M31.3 | — | 3 | 6 | 1 | — | 9 |
Kidney transplantation | D016030 | — | — | 2 | — | 2 | 3 | — | 7 |
Autoimmune hepatitis | D019693 | — | K75.4 | — | 2 | — | 3 | 2 | 7 |
Vasculitis | D014657 | HP_0002633 | — | — | 2 | 4 | 2 | — | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Anti-neutrophil cytoplasmic antibody-associated vasculitis | D056648 | — | I77.82 | — | 4 | 3 | — | 2 | 9 |
Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | 3 | — | 1 | — | 2 | 6 |
Neuromyelitis optica | D009471 | EFO_0004256 | G36.0 | — | 2 | 4 | — | 1 | 5 |
Renal insufficiency | D051437 | HP_0000083 | N19 | 1 | — | 2 | — | 1 | 4 |
Liver diseases | D008107 | HP_0002910 | K70-K77 | — | — | 2 | — | 2 | 4 |
Thrombocytopenia | D013921 | HP_0001873 | D69.6 | — | 1 | 2 | — | — | 3 |
Interstitial lung diseases | D017563 | HP_0006530 | J84.89 | — | 1 | 1 | — | 1 | 3 |
Pulmonary fibrosis | D011658 | — | J84.10 | — | 1 | 3 | — | — | 3 |
Eosinophilic granuloma | D004803 | — | C96.6 | — | — | 3 | — | — | 3 |
Bronchiolitis obliterans | D001989 | EFO_0007183 | — | — | — | 2 | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sickle cell anemia | D000755 | EFO_0000697 | D57 | 1 | 2 | — | — | 1 | 4 |
Idiopathic pulmonary fibrosis | D054990 | — | J84.112 | 1 | 2 | — | — | 2 | 4 |
Pemphigus | D010392 | EFO_1000749 | L10 | — | 2 | — | — | — | 2 |
Diffuse scleroderma | D045743 | EFO_0000404 | — | — | 2 | — | — | — | 2 |
Eye diseases | D005128 | EFO_0003966 | H44 | — | 1 | — | — | — | 1 |
Chronic urticaria | D000080223 | — | L50.8 | 1 | 1 | — | — | — | 1 |
Iga vasculitis | D011695 | EFO_1000965 | D69.0 | — | 1 | — | — | — | 1 |
Adult-onset still's disease | D016706 | EFO_0007135 | M06.1 | — | 1 | — | — | — | 1 |
Behcet syndrome | D001528 | EFO_0003780 | M35.2 | — | 1 | — | — | — | 1 |
Bullous pemphigoid | D010391 | EFO_0007187 | L12 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | — | — | — | 3 | 3 |
Autoimmune diseases | D001327 | HP_0002960 | M30-M36 | — | — | — | — | 2 | 2 |
Systemic scleroderma | D012595 | EFO_0000717 | M34 | — | — | — | — | 2 | 2 |
Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | — | 1 | 1 |
Choroidal neovascularization | D020256 | — | — | — | — | — | — | 1 | 1 |
Squamous intraepithelial lesions | D000081483 | — | — | — | — | — | — | 1 | 1 |
Scleritis | D015423 | HP_0100534 | H15.0 | — | — | — | — | 1 | 1 |
Herpes zoster | D006562 | EFO_0006510 | B02 | — | — | — | — | 1 | 1 |
Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | — | — | — | — | 1 | 1 |
Arthritis | D001168 | HP_0001369 | M05-M14 | — | — | — | — | 1 | 1 |
Drug common name | Azathioprine |
INN | azathioprine |
Description | Azathioprine is a thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. It has a role as an antineoplastic agent, an antimetabolite, an immunosuppressive agent, a prodrug, a carcinogenic agent, a DNA synthesis inhibitor and a hepatotoxic agent. It is a thiopurine, a C-nitro compound, a member of imidazoles and an aryl sulfide. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | Cn1cnc([N+](=O)[O-])c1Sc1ncnc2[nH]cnc12 |
PDB | — |
CAS-ID | 446-86-6 |
RxCUI | — |
ChEMBL ID | CHEMBL1542 |
ChEBI ID | 2948 |
PubChem CID | 2265 |
DrugBank | DB00993 |
UNII ID | MRK240IY2L (ChemIDplus, GSRS) |