Tradename | Company | Number | Date | Products |
---|---|---|---|---|
IMURAN | Sebela Pharmaceuticals | N-016324 RX | 1982-01-01 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
IMURAN | Casper Pharma | N-017391 DISCN | 1982-01-01 | 1 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
azasan | ANDA | 2024-10-17 |
azathioprine | ANDA | 2025-07-01 |
azathioprine sodium | ANDA | 2025-01-23 |
imuran | New Drug Application | 2024-07-20 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Crohn disease | D003424 | EFO_0000384 | K50 | — | 3 | 14 | 13 | 22 | 52 |
Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | 2 | 3 | 7 | 13 | 25 |
Inflammatory bowel diseases | D015212 | EFO_0003767 | — | 1 | — | 1 | 4 | 18 | 24 |
Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | 4 | 7 | 6 | 2 | 4 | 21 |
Nephritis | D009393 | — | N05 | 1 | 6 | 9 | 2 | 4 | 21 |
Lupus nephritis | D008181 | EFO_0005761 | — | 1 | 6 | 8 | 2 | 4 | 20 |
Vasculitis | D014657 | EFO_0006803 | M31 | — | 6 | 10 | 3 | 2 | 20 |
Colitis | D003092 | EFO_0003872 | K52.9 | — | 2 | 3 | 7 | 8 | 20 |
Intestinal diseases | D007410 | — | K63.9 | 1 | — | — | 3 | 11 | 15 |
Ulcer | D014456 | MPATH_579 | — | — | 2 | 3 | 4 | 6 | 15 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pulmonary fibrosis | D011658 | — | J84.10 | 1 | 3 | 3 | — | 2 | 7 |
Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | 3 | — | 1 | — | 2 | 6 |
Fibrosis | D005355 | — | — | 1 | 2 | 2 | — | 2 | 6 |
Renal insufficiency | D051437 | — | N19 | 2 | — | 2 | — | 1 | 5 |
Idiopathic pulmonary fibrosis | D054990 | — | J84.112 | 1 | 2 | 1 | — | 2 | 5 |
Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | — | 2 | — | 2 | 4 |
Inflammation | D007249 | MP_0001845 | — | — | — | 2 | — | 2 | 4 |
Bronchiolitis obliterans syndrome | D000092122 | — | D89.811 | — | 1 | 2 | — | — | 3 |
Eosinophilic granuloma | D004803 | — | C96.6 | — | — | 3 | — | — | 3 |
Chronic renal insufficiency | D051436 | — | N18 | — | 1 | 1 | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sclerosis | D012598 | — | — | — | 2 | — | — | 3 | 5 |
Sickle cell anemia | D000755 | EFO_0000697 | D57 | 1 | 2 | — | — | 1 | 4 |
Systemic scleroderma | D012595 | EFO_0000717 | M34 | — | 2 | — | — | 2 | 4 |
Diffuse scleroderma | D045743 | EFO_0000404 | — | — | 2 | — | — | 2 | 4 |
Bullous pemphigoid | D010391 | EFO_0007187 | L12 | — | 2 | — | — | — | 2 |
Eye diseases | D005128 | EFO_0003966 | H44 | — | 1 | — | — | — | 1 |
Chronic urticaria | D000080223 | — | L50.8 | 1 | 1 | — | — | — | 1 |
Urticaria | D014581 | EFO_0005531 | L50 | 1 | 1 | — | — | — | 1 |
Iga vasculitis | D011695 | EFO_1000965 | D69.0 | — | 1 | — | — | — | 1 |
Vascular skin diseases | D017445 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Dermatitis | D003872 | — | L30.9 | 1 | — | — | — | 5 | 6 |
Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Cutaneous lupus erythematosus | D008178 | EFO_0003834 | L93.1 | 1 | — | — | — | — | 1 |
Photosensitivity disorders | D010787 | — | L57.1 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | — | — | — | 4 | 4 |
Autoimmune diseases | D001327 | EFO_0000540 | M30-M36 | — | — | — | — | 3 | 3 |
Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | — | — | — | 2 | 2 |
Genetic polymorphism | D011110 | — | — | — | — | — | — | 2 | 2 |
Choroidal neovascularization | D020256 | — | — | — | — | — | — | 1 | 1 |
Pathologic neovascularization | D009389 | — | — | — | — | — | — | 1 | 1 |
Squamous intraepithelial lesions | D000081483 | — | — | — | — | — | — | 1 | 1 |
Retinal diseases | D012164 | — | H35.9 | — | — | — | — | 1 | 1 |
Scleritis | D015423 | — | H15.0 | — | — | — | — | 1 | 1 |
Lipidoses | D008064 | — | E75.6 | — | — | — | — | 1 | 1 |
Drug common name | Azathioprine |
INN | azathioprine |
Description | Azathioprine is a thiopurine that is 6-mercaptopurine in which the mercapto hydrogen is replaced by a 1-methyl-4-nitroimidazol-5-yl group. It is a prodrug for mercaptopurine and is used as an immunosuppressant, prescribed for the treatment of inflammatory conditions and after organ transplantation and also for treatment of Crohn's didease and MS. It has a role as an antineoplastic agent, an antimetabolite, an immunosuppressive agent, a prodrug, a carcinogenic agent, a DNA synthesis inhibitor and a hepatotoxic agent. It is a thiopurine, a C-nitro compound, a member of imidazoles and an aryl sulfide. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Cn1cnc([N+](=O)[O-])c1Sc1ncnc2[nH]cnc12 |
PDB | — |
CAS-ID | 446-86-6 |
RxCUI | — |
ChEMBL ID | CHEMBL1542 |
ChEBI ID | 2948 |
PubChem CID | 2265 |
DrugBank | DB00993 |
UNII ID | MRK240IY2L (ChemIDplus, GSRS) |