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Drug ReportsAzatadine
Azatadine
Optimine, Trinalin (azatadine) is a small molecule pharmaceutical. Azatadine was first approved as Optimine on 1982-01-01. It is used to treat allergic rhinitis perennial, allergic rhinitis seasonal, ear diseases, respiration disorders, and urticaria in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
skin and connective tissue diseasesD017437
immune system diseasesD007154
Trade Name
FDA
EMA
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Drug Products
FDA
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Azatadine maleate
Tradename
Company
Number
Date
Products
OPTIMINEMerck & CoN-017601 DISCN1982-01-01
1 products
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Azatadine maleate
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Pseudoephedrine sulfate
Tradename
Company
Number
Date
Products
TRINALINMerck & CoN-018506 DISCN1982-03-23
1 products
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Labels
FDA
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Agency Specific
FDA
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ATC Codes
R: Respiratory system drugs
R06: Antihistamines for systemic use
R06A: Antihistamines for systemic use
R06AX: Other antihistamines for systemic use in atc
R06AX09: Azatadine
HCPCS
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Clinical
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Drug
General
Drug common nameAzatadine
INNazatadine
Description
Azatadine is a benzo[5,6]cyclohepta[1,2-b]pyridine having a 1-methylpiperidin-4-ylidene group at the 11-position. It has a role as a H1-receptor antagonist and an anti-allergic agent. It is a benzocycloheptapyridine and a tertiary amine.
Classification
Small molecule
Drug classtricyclic histaminic-H1 receptor antagonists, loratadine derivatives (formerly-tadine)
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Structure (InChI/SMILES or Protein Sequence)
CN1CCC(=C2c3ccccc3CCc3cccnc32)CC1
Identifiers
PDB
CAS-ID3964-81-6
RxCUI
ChEMBL IDCHEMBL946
ChEBI ID2946
PubChem CID19861
DrugBankDB00719
UNII ID94Z39NID6C (ChemIDplus, GSRS)
Target
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Variants
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Financial
Revenue by drug
$
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Estimated US medical usage
Azatadine
Total medical expenditures per year (USD, in millions)
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Azatadine
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Pseudoephedrine
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
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Additional graphs summarizing 97 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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16 adverse events reported
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