Avoralstat
Avoralstat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target plasma kallikrein.
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Commercial
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Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hereditary angioedemas | D054179 | EFO_0004131 | — | 2 | 2 | 2 | — | — | 5 |
| Angioedema | D000799 | EFO_0005532 | T78.3 | 2 | 2 | 2 | — | — | 5 |
Indications Phases 2
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Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Avoralstat |
| INN | avoralstat |
| Description | Avoralstat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target plasma kallikrein. |
| Classification | Small molecule |
| Drug class | enzyme inhibitors: 1) kallikrein inhibitors or 2) serine protease inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=Cc1cc(C(=O)Nc2ccc(C(=N)N)cc2)c(-c2ccc(C(=O)NCC3CC3)nc2C(=O)O)cc1OC |
Identifiers
| PDB | — |
| CAS-ID | 918407-35-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297502 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | UX17773O15 (ChemIDplus, GSRS) |
Target
Agency Approved
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Variants
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Trends
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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