Aviptadil - PharmaKB

Aviptadil

Aviptadil is a protein pharmaceutical. It is currently being investigated in clinical studies.

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COVID-19

Events Timeline

Commercial

Clinical

Drug

Target

Variants

Financial

Trends

Safety

Events Timeline

YTD

Max

Events

FDA approval date

EMA approval date

Patent expiration date

Study first post date

Last update post date

Start date

Primary completion date

Completion date

Results first post date

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Commercial

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Clinical

Clinical Trials

14 clinical trials

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Indications Phases 4

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Indications Phases 3

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Covid-19	D000086382	—	U07.1	—	6	4	—	—	8
Respiratory distress syndrome	D012128	EFO_1000637	J80	—	4	3	—	—	5
Respiratory insufficiency	D012131	—	J96.9	—	3	1	—	1	4
Acute lung injury	D055371	EFO_0004610	—	—	3	3	—	—	4
Coronavirus infections	D018352	EFO_0007224	B34.2	—	2	2	—	—	3
Sars-cov-2	D000086402	—	—	—	2	2	—	—	3
Newborn respiratory distress syndrome	D012127	—	P22	—	2	2	—	—	3
Virus diseases	D014777	—	B34	—	1	1	—	—	2
Dyspnea	D004417	—	R06.0	—	1	2	—	—	2
Lung injury	D055370	—	S27.30	—	1	2	—	—	2

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Indications Phases 2

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Heart failure	D006333	EFO_0003144	I50	—	1	—	—	1	2
Disease	D004194	EFO_0000408	R69	—	1	—	—	—	1
Cytokine release syndrome	D000080424	—	D89.83	—	1	—	—	—	1
Cardiovascular diseases	D002318	EFO_0000319	I98	—	1	—	—	—	1
Myocardial infarction	D009203	EFO_0000612	I21	—	1	—	—	—	1
Coronavirus	D017934	—	—	—	1	—	—	—	1
Pneumonia	D011014	EFO_0003106	J18	—	1	—	—	—	1
Inflammation	D007249	MP_0001845	—	—	1	—	—	—	1
Syndrome	D013577	—	—	—	1	—	—	—	1
Pulmonary edema	D011654	EFO_1001134	J81	—	1	—	—	—	1

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Indications Phases 1

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Indications Without Phase

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Spinal cord injuries	D013119	EFO_1001919	—	—	—	—	—	2	2
Human milk	D008895	—	—	—	—	—	—	1	1
Depression	D003863	—	F33.9	—	—	—	—	1	1

Epidemiology

Epidemiological information for investigational and approved indications

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Drug

General

Drug common name	Aviptadil
INN	aviptadil
Description	AVIPTADIL
Classification	Protein
Drug class	vasodilators (undefined group)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)	CC[C@H](C)[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCCN)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(=O)O)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1cnc[nH]1)C(C)C)[C@@H](C)O)[C@H](O)CC)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)O