Avexitide
Avexitide is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target glucagon-like peptide 1 receptor.
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Commercial
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Clinical
Clinical Trials
41 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 4 | — | — | 2 | 3 | 9 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | 1 | — | 2 | 5 | 8 |
| Insulin secretion | D000078790 | — | — | — | — | — | 1 | — | 1 |
| Prediabetic state | D011236 | EFO_1001121 | R73.03 | — | — | — | 1 | — | 1 |
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | 4 | 1 | — | — | 3 | 8 |
| Hypoglycemia | D007003 | HP_0001943 | E16.2 | 2 | 3 | — | — | 1 | 6 |
| Congenital hyperinsulinism | D044903 | — | — | 1 | 2 | — | — | — | 2 |
| Nesidioblastosis | D046768 | EFO_0007318 | E16.9 | 1 | 2 | — | — | — | 2 |
| Hyperinsulinism | D006946 | HP_0000842 | E16.1 | 2 | 1 | — | — | — | 2 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bariatric surgery | D050110 | — | — | 1 | — | — | — | 1 | 2 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | 1 | 2 |
| Hyperglycemia | D006943 | HP_0003074 | R73.9 | 1 | — | — | — | 1 | 2 |
| Nutrition disorders | D009748 | EFO_0001069 | — | 1 | — | — | — | — | 1 |
| Gastric emptying | D005746 | — | — | 1 | — | — | — | — | 1 |
| Digestive system physiological phenomena | D004068 | — | — | 1 | — | — | — | — | 1 |
| Gastrointestinal motility | D005769 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glucose metabolism disorders | D044882 | — | — | — | — | — | — | 4 | 4 |
| Metabolic diseases | D008659 | EFO_0000589 | E88.9 | — | — | — | — | 4 | 4 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | — | — | 1 | 1 |
| Dumping syndrome | D004377 | EFO_1001307 | K91.1 | — | — | — | — | 1 | 1 |
| Morbid obesity | D009767 | EFO_0001074 | — | — | — | — | — | 1 | 1 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | — | — | 1 | 1 |
| Exploratory behavior | D005106 | EFO_0004316 | — | — | — | — | — | 1 | 1 |
| Appetite regulation | D001069 | — | — | — | — | — | — | 1 | 1 |
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Avexitide |
| INN | avexitide |
| Description | Avexitide is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target glucagon-like peptide 1 receptor. |
| Classification | Protein |
| Drug class | peptides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297949 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 5313W10MYT (ChemIDplus, GSRS) |
Target
Agency Approved
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Variants
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Financial
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Trends
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Additional graphs summarizing 39 documents
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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