Qulipta, Aquipta(atogepant)
Aquipta, Qulipta (atogepant) is a small molecule pharmaceutical. Atogepant was first approved as Qulipta on 2021-09-28. It is used to treat migraine disorders in the USA. It has been approved in Europe to treat migraine disorders.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| nervous system diseases | D009422 |
Trade Name
FDA
EMA
Qulipta
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| qulipta | New Drug Application | 2023-06-01 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| migraine disorders | EFO_0003821 | D008881 | G43 |
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
ATOGEPANT, QULIPTA, ABBVIE | |||
| 2026-09-28 | NCE | ||
| 2026-04-17 | I-909 | ||
HCPCS
No data
Clinical
Clinical Trials
26 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Migraine disorders | D008881 | EFO_0003821 | G43 | 1 | 1 | 15 | 1 | 8 | 25 |
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | — | — | — | — | 1 | 1 |
| Interstitial cystitis | D018856 | EFO_1000869 | N30.1 | — | — | — | — | 1 | 1 |
| Syndrome | D013577 | — | — | — | — | — | — | 1 | 1 |
| Cystitis | D003556 | EFO_1000025 | N30 | — | — | — | — | 1 | 1 |
| Migraine without aura | D020326 | EFO_0005296 | G43.0 | — | — | — | — | 1 | 1 |
| Migraine with aura | D020325 | EFO_0005295 | G43.1 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Atogepant |
| INN | atogepant |
| Description | Atogepant, sold under the brand name QULIPTA, is a medication used to prevent migraines. It is a gepant, an orally active calcitonin gene-related peptide receptor (CGRPR) antagonist.
|
| Classification | Small molecule |
| Drug class | calcitonin gene-related peptide receptor antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@@H]1[C@H](c2c(F)ccc(F)c2F)C[C@H](NC(=O)c2cnc3c(c2)C[C@@]2(C3)C(=O)Nc3ncccc32)C(=O)N1CC(F)(F)F |
Identifiers
| PDB | — |
| CAS-ID | 1374248-81-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3991065 |
| ChEBI ID | — |
| PubChem CID | 72163100 |
| DrugBank | DB16098 |
| UNII ID | 7CRV8RR151 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Qulipta – AbbVie
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Tabular view
Estimated US medical usage
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Trends
PubMed Central
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Additional graphs summarizing 273 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3,254 adverse events reported
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