

Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alcoholism | D000437 | EFO_0003829 | F10.1 | 1 | — | — | — | — | 1 |
| Drug common name | Aticaprant |
| INN | aticaprant |
| Description | Aticaprant, also known by its developmental codes JNJ-67953964, CERC-501, and LY-2456302, is a κ-opioid receptor (KOR) antagonist which is under development for the treatment of major depressive disorder. A regulatory application for approval of the medication is expected to be submitted by 2025. Aticaprant is taken by mouth.
|
| Classification | Small molecule |
| Drug class | kappa opiod receptor antagonists |
| Image (chem structure or protein) | ![]() |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cc(C)cc([C@@H]2CCCN2Cc2ccc(Oc3ccc(C(N)=O)cc3F)cc2)c1 |
| PDB | — |
| CAS-ID | 1174130-61-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1921847 |
| ChEBI ID | — |
| PubChem CID | 44129648 |
| DrugBank | DB12341 |
| UNII ID | DE4G8X55F5 (ChemIDplus, GSRS) |
