Astegolimab
Astegolimab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
10 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | 2 | 2 | — | — | 4 |
| Lung diseases | D008171 | HP_0002088 | J98.4 | — | 1 | 2 | — | — | 3 |
| Obstructive lung diseases | D008173 | HP_0006536 | — | — | 1 | 2 | — | — | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Asthma | D001249 | EFO_0000270 | J45 | 1 | 1 | — | — | — | 2 |
| Disease progression | D018450 | — | — | — | 1 | — | — | — | 1 |
| Covid-19 | D000086382 | — | — | — | 1 | — | — | — | 1 |
| Pneumonia | D011014 | EFO_0003106 | — | — | 1 | — | — | — | 1 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | 1 | — | — | — | 1 |
| Eczema | D004485 | HP_0000964 | L30.9 | — | 1 | — | — | — | 1 |
| Dermatitis | D003872 | HP_0011123 | L30.9 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sinusitis | D012852 | EFO_0007486 | J32 | 1 | — | — | — | — | 1 |
| Nasal polyps | D009298 | HP_0100582 | J33 | 1 | — | — | — | — | 1 |
| Polyps | D011127 | EFO_0000662 | — | 1 | — | — | — | — | 1 |
| Rhinosinusitis | D000096825 | — | — | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Astegolimab |
| INN | astegolimab |
| Description | Astegolimab is a selective ST2 IgG2 monoclonal antibody developed to treat asthma and chronic obstructive pulmonary disease. It is developed by Genentech.
|
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4594385 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 27TW751DTH (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 205 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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