Artemisinin
Artemisinin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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353 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malaria | D008288 | EFO_0001068 | B54 | 25 | 34 | 58 | 81 | 74 | 260 |
| Falciparum malaria | D016778 | EFO_0007444 | B50 | 8 | 33 | 33 | 41 | 29 | 132 |
| Vivax malaria | D016780 | EFO_0007445 | B51 | 1 | 1 | 7 | 7 | 5 | 21 |
| Anemia | D000740 | EFO_0004272 | D64.9 | — | 1 | 2 | 6 | 3 | 11 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 2 | — | 1 | 6 | 1 | 10 |
| Covid-19 | D000086382 | — | U07.1 | — | 4 | 4 | 2 | — | 9 |
| Recurrence | D012008 | — | — | — | — | 1 | 1 | 5 | 7 |
| Hiv | D006678 | — | O98.7 | 2 | — | — | 2 | — | 4 |
| Acquired immunodeficiency syndrome | D000163 | EFO_0000765 | B20 | 1 | — | — | 3 | — | 4 |
| Schistosomiasis | D012552 | EFO_1001475 | B65 | — | 1 | 1 | 1 | — | 3 |
Show 14 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 1 | — | 2 | — | 1 | 4 |
| Fever | D005334 | — | R50.9 | — | — | 1 | — | 3 | 4 |
| Cerebral malaria | D016779 | — | B50.0 | 2 | — | 1 | — | — | 3 |
| Protozoan infections | D011528 | — | B50-B64 | 1 | — | 1 | — | 1 | 3 |
| Coronavirus infections | D018352 | EFO_0007224 | B34.2 | — | 1 | 1 | — | — | 2 |
| Schistosomiasis haematobia | D012553 | EFO_0007530 | B65.0 | — | 1 | 1 | — | — | 2 |
| Communicable diseases | D003141 | — | — | — | — | 1 | — | 1 | 2 |
| Cytomegalovirus infections | D003586 | EFO_0001062 | B25 | — | 1 | 1 | — | — | 2 |
| Glucosephosphate dehydrogenase deficiency | D005955 | EFO_0007287 | — | — | 1 | 2 | — | — | 2 |
| Asymptomatic diseases | D058070 | — | — | — | 1 | 1 | — | 1 | 2 |
Show 15 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Papillomavirus infections | D030361 | — | — | — | 4 | — | — | — | 4 |
| Squamous intraepithelial lesions of the cervix | D065310 | — | — | 1 | 2 | — | — | — | 3 |
| Healthy volunteers/patients | — | — | — | 3 | 1 | — | — | — | 3 |
| Neoplasms | D009369 | — | C80 | 2 | 1 | — | — | — | 2 |
| Carcinoma in situ | D002278 | — | D09.9 | 1 | 1 | — | — | — | 2 |
| Precancerous conditions | D011230 | — | — | 1 | 1 | — | — | — | 2 |
| Colorectal neoplasms | D015179 | — | — | — | 2 | — | — | — | 2 |
| Bone neoplasms | D001859 | EFO_0003820 | D16 | — | 2 | — | — | — | 2 |
| Combination drug therapy | D004359 | — | — | 2 | 1 | — | — | — | 2 |
| Pharmacokinetics | D010599 | — | — | 2 | 1 | — | — | — | 2 |
Show 15 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Parasitemia | D018512 | — | — | 1 | — | — | — | 3 | 4 |
| Papillomaviridae | D027383 | — | — | 1 | — | — | — | 1 | 2 |
| Papilloma | D010212 | — | — | 1 | — | — | — | — | 1 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | — | — | — | — | 1 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | — | — | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | — | — | — | 1 |
| Pulmonary arterial hypertension | D000081029 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Drug resistance | D004351 | — | Z16.30 | — | — | — | — | 2 | 2 |
| Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | — | 2 | 2 |
| Retinal diseases | D012164 | — | H35.9 | — | — | — | — | 1 | 1 |
| Diabetic retinopathy | D003930 | EFO_0003770 | — | — | — | — | — | 1 | 1 |
| Epidemiologic studies | D016021 | — | — | — | — | — | — | 1 | 1 |
| Psychotic disorders | D011618 | — | F20.81 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Artemisinin |
| INN | artemisinin |
| Description | (+)-artemisinin is a sesquiterpene lactone obtained from sweet wormwood, Artemisia annua, which is used as an antimalarial for the treatment of multi-drug resistant strains of falciparum malaria. It has a role as an antimalarial and a plant metabolite. It is a sesquiterpene lactone and an organic peroxide. |
| Classification | Small molecule |
| Drug class | antimalarials (artemisin derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C[C@@H]1CC[C@H]2[C@@H](C)C(=O)O[C@@H]3O[C@]4(C)CC[C@@H]1[C@]32OO4 |
Identifiers
| PDB | — |
| CAS-ID | 63968-64-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL567597 |
| ChEBI ID | — |
| PubChem CID | 68827 |
| DrugBank | — |
| UNII ID | 9RMU91N5K2 (ChemIDplus, GSRS) |
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Safety
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10 adverse events reported
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