Arginine
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865 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypertension | D006973 | EFO_0000537 | I10 | 6 | 6 | 6 | 7 | 15 | 38 |
| Healthy volunteers/patients | — | — | — | 11 | 2 | 1 | 4 | 22 | 38 |
| Shock | D012769 | — | R57.1 | 1 | 7 | 6 | 6 | 7 | 23 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 4 | 2 | 1 | 4 | 12 | 22 |
| Nocturia | D053158 | — | R35.1 | — | 7 | 10 | 2 | 4 | 22 |
| Diabetes insipidus | D003919 | — | E23.2 | 1 | 4 | 2 | 1 | 14 | 22 |
| Cardiovascular diseases | D002318 | HP_0001626 | — | 5 | 2 | 1 | 1 | 13 | 21 |
| Hemorrhage | D006470 | MP_0001914 | R58 | 2 | 7 | 1 | 10 | 1 | 20 |
| Covid-19 | D000086382 | — | — | 1 | 2 | 4 | 1 | 11 | 19 |
| Nocturnal enuresis | D053206 | — | N39.44 | — | — | 3 | 9 | 7 | 19 |
Show 112 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | 2 | 7 | 2 | — | 23 | 32 |
| Neoplasms | D009369 | — | C80 | 15 | 5 | 2 | — | 5 | 23 |
| Carcinoma | D002277 | — | C80.0 | 7 | 5 | 2 | — | 4 | 16 |
| Dental caries | D003731 | EFO_0003819 | K02 | 1 | 3 | 1 | — | 10 | 15 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 3 | 5 | 5 | — | 1 | 12 |
| Wounds and injuries | D014947 | — | T14.8 | 2 | 3 | 1 | — | 7 | 12 |
| Fibrosis | D005355 | — | — | 2 | 2 | 1 | — | 6 | 10 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | 2 | 1 | 1 | — | 6 | 9 |
| Insulin resistance | D007333 | HP_0000855 | — | 1 | — | 1 | — | 6 | 8 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 3 | 3 | 3 | — | 1 | 8 |
Show 66 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 1 | 3 | — | — | 6 | 9 |
| Non-small-cell lung carcinoma | D002289 | — | — | 5 | 3 | — | — | 2 | 8 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 4 | 4 | — | — | 3 | 8 |
| Prostatic neoplasms | D011471 | — | C61 | 4 | 4 | — | — | 1 | 8 |
| Melanoma | D008545 | — | — | 6 | 3 | — | — | — | 8 |
| Lymphoma | D008223 | — | C85.9 | 4 | 3 | — | — | 1 | 7 |
| Squamous cell carcinoma | D002294 | — | — | 4 | 1 | — | — | 2 | 6 |
| Leukemia | D007938 | — | C95 | 4 | 3 | — | — | 1 | 6 |
| Lung neoplasms | D008175 | HP_0100526 | C34.90 | 5 | 3 | — | — | — | 6 |
| Urinary bladder neoplasms | D001749 | — | C67 | 1 | 1 | — | — | 4 | 6 |
Show 111 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 1 | — | — | — | 8 | 9 |
| Pressure ulcer | D003668 | — | — | 1 | — | — | — | 6 | 7 |
| Lung diseases | D008171 | HP_0002088 | J98.4 | 1 | — | — | — | 5 | 6 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 3 | — | — | — | 2 | 5 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | 2 | — | — | — | 3 | 5 |
| Obstructive lung diseases | D008173 | HP_0006536 | — | 1 | — | — | — | 3 | 4 |
| Premature birth | D047928 | EFO_0003917 | O60 | 1 | — | — | — | 3 | 4 |
| Heart disease risk factors | D000082742 | — | — | 4 | — | — | — | — | 4 |
| Therapeutic equivalency | D013810 | — | — | 4 | — | — | — | — | 4 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | — | — | — | 2 | 3 |
Show 46 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | — | — | — | 8 | 8 |
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | — | — | 7 | 7 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | — | — | — | — | 5 | 5 |
| Diet therapy | D004035 | — | — | — | — | — | — | 4 | 4 |
| Communicable diseases | D003141 | — | — | — | — | — | — | 4 | 4 |
| Postoperative complications | D011183 | — | — | — | — | — | — | 4 | 4 |
| Burns | D002056 | — | T30.0 | — | — | — | — | 4 | 4 |
| Polydipsia | D059606 | HP_0001959 | R63.1 | — | — | — | — | 4 | 4 |
| Musculoskeletal diseases | D009140 | — | — | — | — | — | — | 3 | 3 |
| Musculoskeletal pain | D059352 | — | — | — | — | — | — | 3 | 3 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
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Estimated US medical usage
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Arginine
Total medical expenditures per year (USD, in millions)
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Safety
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Adverse Events
Top Adverse Reactions
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120,718 adverse events reported
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