Arginine
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Clinical Trials
708 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 9 | — | — | 2 | 15 | 26 |
| Nocturia | D053158 | — | R35.1 | — | 6 | 10 | 2 | 4 | 21 |
| Hypertension | D006973 | EFO_0000537 | I10 | 5 | 4 | 1 | 3 | 6 | 18 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 4 | 2 | — | 4 | 9 | 18 |
| Septic shock | D012772 | — | A48.3 | 1 | 3 | 3 | 4 | 6 | 15 |
| Nocturnal enuresis | D053206 | — | N39.44 | — | — | 3 | 7 | 5 | 15 |
| Obesity | D009765 | EFO_0001073 | E66.9 | 2 | 2 | 1 | 1 | 8 | 14 |
| Sickle cell anemia | D000755 | EFO_0000697 | D57 | 2 | 6 | 3 | 1 | 1 | 11 |
| Covid-19 | D000086382 | — | U07.1 | 1 | 1 | 4 | 1 | 3 | 10 |
| Neuroendocrine tumors | D018358 | EFO_1001901 | D3A.8 | 4 | 4 | 2 | 1 | — | 10 |
Show 54 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cardiovascular diseases | D002318 | HP_0001626 | — | 5 | 2 | 1 | — | 7 | 14 |
| Neoplasms | D009369 | — | C80 | 9 | 4 | 2 | — | 2 | 13 |
| Dental caries | D003731 | EFO_0003819 | K02 | — | 3 | 1 | — | 6 | 10 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 3 | 5 | 3 | — | — | 9 |
| Heart failure | D006333 | HP_0001635 | I50 | 2 | 1 | 1 | — | 2 | 6 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 3 | 2 | 3 | — | — | 6 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | 1 | 1 | — | 5 | 6 |
| Asthma | D001249 | EFO_0000270 | J45 | — | 4 | 1 | — | 2 | 6 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | — | 1 | — | 4 | 5 |
| Sepsis | D018805 | HP_0100806 | A41.9 | 1 | 2 | 3 | — | 1 | 5 |
Show 38 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 5 | 3 | — | — | — | 6 |
| Melanoma | D008545 | — | — | 4 | 3 | — | — | — | 6 |
| Colorectal neoplasms | D015179 | — | — | 1 | 3 | — | — | 2 | 5 |
| Schizophrenia | D012559 | EFO_0000692 | F20 | — | 1 | — | — | 4 | 5 |
| Prostatic neoplasms | D011471 | — | C61 | 2 | 3 | — | — | — | 5 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 3 | 3 | — | — | 1 | 5 |
| Regional blood flow | D012039 | — | — | 1 | 3 | — | — | 1 | 5 |
| Ocular physiological phenomena | D009799 | — | — | 1 | 3 | — | — | 1 | 5 |
| Pulmonary hypertension | D006976 | EFO_0001361 | I27.20 | 1 | 1 | — | — | 2 | 4 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | 2 | 2 | — | — | 1 | 4 |
Show 67 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 1 | — | — | — | 5 | 6 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 3 | — | — | — | 2 | 5 |
| Pressure ulcer | D003668 | — | L89 | 1 | — | — | — | 4 | 5 |
| Peripheral vascular diseases | D016491 | EFO_0003875 | I73.9 | 2 | — | — | — | 2 | 4 |
| Heart disease risk factors | D000082742 | — | — | 4 | — | — | — | — | 4 |
| Vasoconstriction | D014661 | — | — | 3 | — | — | — | — | 3 |
| Blood pressure | D001794 | EFO_0004325 | — | 1 | — | — | — | 2 | 3 |
| Dyspnea | D004417 | HP_0002094 | R06.0 | 1 | — | — | — | 1 | 2 |
| Uveal neoplasms | D014604 | EFO_1001230 | — | 2 | — | — | — | — | 2 |
| Social psychology | D011593 | — | — | 2 | — | — | — | — | 2 |
Show 28 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | — | — | — | — | 4 | 4 |
| Diet therapy | D004035 | — | — | — | — | — | — | 4 | 4 |
| Sarcopenia | D055948 | EFO_1000653 | M62.84 | — | — | — | — | 4 | 4 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | — | — | 4 | 4 |
| Fatigue | D005221 | HP_0012378 | R53.83 | — | — | — | — | 3 | 3 |
| Overweight | D050177 | — | E66.3 | — | — | — | — | 3 | 3 |
| Diabetes insipidus | D003919 | — | E23.2 | — | — | — | — | 3 | 3 |
| Hematologic diseases | D006402 | EFO_0005803 | D75.9 | — | — | — | — | 2 | 2 |
| Von willebrand diseases | D014842 | EFO_0003910 | D68.0 | — | — | — | — | 2 | 2 |
| Cerebral palsy | D002547 | — | G80 | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
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Estimated US medical usage
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Arginine
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Safety
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Adverse Events
Top Adverse Reactions
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91,338 adverse events reported
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