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Drug ReportsApelin
Apelin
Apelin is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Drug
Target
Variants
Financial
Trends
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Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
34 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypertensionD006973EFO_0000537I101124
Pulmonary hypertensionD006976EFO_0001361I27.20123
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.9112
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ObesityD009765EFO_0001073E66.91123
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Heart failureD006333HP_0001635I50134
Diabetes mellitusD003920HP_0000819E08-E131124
Cardiovascular diseasesD002318HP_0001626123
Type 2 diabetes mellitusD003924EFO_0001360E11112
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Insulin resistanceD007333HP_0000855213
Healthy volunteers/patients33
Pulmonary arterial hypertensionD000081029112
Familial primary pulmonary hypertensionD065627I27.011
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Heart diseasesD006331EFO_0003777I51.944
VasodilationD01466433
Atrial fibrillationD001281EFO_0000275I48.033
Morbid obesityD009767EFO_000107422
Gestational diabetesD016640HP_0009800O24.422
Kidney diseasesD007674EFO_0003086N0822
Coronary artery diseaseD003324I25.122
Myocardial ischemiaD017202EFO_1001375I20-I2522
Covid-19D00008638211
Renin-angiotensin systemD01208411
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameApelin
INN
Description
Apelin (also known as APLN) is a peptide that in humans is encoded by the APLN gene. Apelin is one of two endogenous ligands for the G-protein-coupled APJ receptor that is expressed at the surface of some cell types. It is widely expressed in various organs such as the heart, lung, kidney, liver, adipose tissue, gastrointestinal tract, brain, adrenal glands, endothelium, and human plasma.
Classification
Unknown
Drug class
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB2LOT, 2LOU, 2LOV, 2LOW, 5VBL, 6KNM, 7SUS, 7W0L, 7W0M, 7W0N, 7W0O, 7W0P, 8XZF, 8XZH, 8XZI, 8XZJ
CAS-ID
RxCUI
ChEMBL IDCHEMBL4650373
ChEBI ID
PubChem CID
DrugBank
UNII ID
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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