Catequentinib
Catequentinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
428 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | 5 | 20 | 8 | 1 | 3 | 33 |
| Thyroid neoplasms | D013964 | EFO_0003841 | — | — | 3 | 2 | 1 | 1 | 5 |
| Thyroid diseases | D013959 | — | E00-E07 | — | 2 | 2 | 1 | 1 | 4 |
| Papillary thyroid cancer | D000077273 | — | — | — | 1 | 1 | 1 | — | 2 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lung neoplasms | D008175 | — | C34.90 | 7 | 27 | 10 | — | 1 | 38 |
| Carcinoma | D002277 | — | C80.0 | 2 | 12 | 4 | — | — | 16 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 2 | 5 | 2 | — | — | 8 |
| Small cell lung carcinoma | D055752 | — | — | — | 4 | 3 | — | — | 7 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | 4 | 1 | — | — | 6 |
| Colorectal neoplasms | D015179 | — | — | 1 | 3 | 2 | — | — | 5 |
| Adenocarcinoma | D000230 | — | — | 1 | 3 | 1 | — | — | 4 |
| Endometrial neoplasms | D016889 | EFO_0004230 | — | — | 3 | 1 | — | — | 4 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | 4 | 1 | — | — | 4 |
| Sarcoma | D012509 | — | — | — | 3 | 2 | — | — | 4 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 6 | 8 | — | — | — | 13 |
| Recurrence | D012008 | — | — | 1 | 6 | — | — | — | 6 |
| Gastrointestinal neoplasms | D005770 | — | C26.9 | — | 5 | — | — | — | 5 |
| Digestive system neoplasms | D004067 | — | — | — | 5 | — | — | — | 5 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 3 | — | — | — | 3 |
| Squamous cell carcinoma | D002294 | — | — | — | 3 | — | — | — | 3 |
| Esophageal squamous cell carcinoma | D000077277 | — | — | — | 3 | — | — | — | 3 |
| Esophageal neoplasms | D004938 | — | C15 | — | 3 | — | — | — | 3 |
| Gastrointestinal diseases | D005767 | — | — | — | 3 | — | — | — | 3 |
| Digestive system diseases | D004066 | EFO_0000405 | K92.9 | — | 3 | — | — | — | 3 |
Show 23 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Catequentinib |
| INN | catequentinib |
| Description | Anlotinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target vascular endothelial growth factor receptor 2, vascular endothelial growth factor receptor 3, fibroblast growth factor receptor 1, and vascular endothelial growth factor receptor 1. |
| Classification | Small molecule |
| Drug class | tyrosine kinase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ccnc2cc1OCC1(N)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 1058156-90-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4303201 |
| ChEBI ID | — |
| PubChem CID | 25017411 |
| DrugBank | DB11885 |
| UNII ID | GKF8S4C432 (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
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241 adverse events reported
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