Amrubicin
Amrubicin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
25 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Small cell lung carcinoma | D055752 | — | — | 1 | 6 | 6 | — | — | 13 |
| Lung neoplasms | D008175 | — | C34.90 | 2 | 5 | 5 | — | — | 12 |
| Neoplasms | D009369 | — | C80 | 2 | — | 1 | — | — | 3 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | 2 | — | — | — | 2 |
| Multiple myeloma | D009101 | — | C90.0 | 1 | 1 | — | — | — | 1 |
| Urinary bladder neoplasms | D001749 | — | C67 | — | 1 | — | — | — | 1 |
| Transitional cell carcinoma | D002295 | — | — | — | 1 | — | — | — | 1 |
| Thymoma | D013945 | — | — | — | 1 | — | — | — | 1 |
| Thymus neoplasms | D013953 | — | C37 | — | 1 | — | — | — | 1 |
| Sarcoma | D012509 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Amrubicin |
| INN | amrubicin |
| Description | Amrubicin (INN; previously known as SM-5887) is an anthracycline used in the treatment of lung cancer. It is marketed in Japan since 2002 by Sumitomo under the brand name Calsed.
|
| Classification | Small molecule |
| Drug class | antineoplastic antibiotics (daunorubicin type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)[C@]1(N)Cc2c(O)c3c(c(O)c2[C@@H](O[C@H]2C[C@H](O)[C@H](O)CO2)C1)C(=O)c1ccccc1C3=O |
Identifiers
| PDB | — |
| CAS-ID | 110267-81-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1186894 |
| ChEBI ID | — |
| PubChem CID | 178149 |
| DrugBank | — |
| UNII ID | 93N13LB4Z2 (ChemIDplus, GSRS) |
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Safety
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206 adverse events reported
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