Ampreloxetine
Ampreloxetine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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EMA approval date
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Study first post date
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Commercial
No data
Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Orthostatic hypotension | D007024 | — | I95.1 | 2 | 1 | 4 | — | — | 7 |
| Hypotension | D007022 | EFO_0005251 | I95 | — | 1 | 3 | — | — | 4 |
| Pure autonomic failure | D054970 | — | — | — | 1 | 3 | — | — | 4 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | 1 | 1 | — | — | 2 |
| Multiple system atrophy | D019578 | — | — | — | 1 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Myofascial pain syndromes | D009209 | EFO_1001054 | — | 1 | 1 | — | — | — | 2 |
| Fibromyalgia | D005356 | EFO_0005687 | M79.1 | 1 | 1 | — | — | — | 2 |
| Shy-drager syndrome | D012791 | EFO_1001050 | — | — | 1 | — | — | — | 1 |
| Atrophy | D001284 | — | — | — | 1 | — | — | — | 1 |
| Hyperkinesis | D006948 | — | — | — | 1 | — | — | — | 1 |
| Attention deficit disorder with hyperactivity | D001289 | EFO_0003888 | F90 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Ampreloxetine |
| INN | ampreloxetine |
| Description | Ampreloxetine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | antidepressants (fluoxetine type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Fc1cc(F)c(OCc2ccccc2C2CCNCC2)c(F)c1 |
Identifiers
| PDB | — |
| CAS-ID | 1227056-84-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297646 |
| ChEBI ID | — |
| PubChem CID | 46189893 |
| DrugBank | DB15348 |
| UNII ID | 19997EZ42I (ChemIDplus, GSRS) |
Target
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Variants
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Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 33 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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