Brand Name | Status | Last Update |
---|---|---|
ethyol | New Drug Application | 2023-11-02 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
experimental radiation injuries | — | D011833 | — |
Code | Description |
---|---|
J0207 | Injection, amifostine, 500 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Head and neck neoplasms | D006258 | — | — | 4 | 13 | 1 | 1 | 1 | 16 |
Lung neoplasms | D008175 | HP_0100526 | C34.90 | 3 | 10 | 1 | 1 | 1 | 14 |
Neoplasms | D009369 | — | C80 | 6 | 5 | 1 | 1 | 1 | 13 |
Lymphoma | D008223 | — | C85.9 | 3 | 4 | — | 1 | — | 7 |
Stomatitis | D013280 | EFO_1001904 | K12.1 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 3 | 8 | 1 | — | — | 10 |
Multiple myeloma | D009101 | — | C90.0 | 1 | — | 1 | — | — | 2 |
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 1 | — | 1 | — | — | 2 |
Peripheral nervous system diseases | D010523 | HP_0009830 | G64 | — | — | 1 | — | — | 1 |
Trophoblastic neoplasms | D014328 | — | — | — | — | 1 | — | — | 1 |
Trigeminal neuralgia | D014277 | EFO_1001219 | G50.0 | — | — | 1 | — | — | 1 |
Squamous cell carcinoma of head and neck | D000077195 | — | — | — | — | 1 | — | — | 1 |
Hepatoblastoma | D018197 | — | C22.2 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myelodysplastic syndromes | D009190 | — | D46 | 2 | 8 | — | — | — | 9 |
Leukemia | D007938 | — | C95 | 6 | 6 | — | — | — | 9 |
Sarcoma | D012509 | — | — | 2 | 4 | — | — | — | 5 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 4 | — | — | — | 5 |
Central nervous system neoplasms | D016543 | — | — | 1 | 2 | — | — | — | 3 |
Mucositis | D052016 | EFO_1001898 | — | — | 3 | — | — | — | 3 |
Prostatic neoplasms | D011471 | — | C61 | — | 3 | — | — | — | 3 |
Uterine cervical neoplasms | D002583 | HP_0030159 | — | 2 | 2 | — | — | — | 3 |
Colorectal neoplasms | D015179 | — | — | 1 | 2 | — | — | — | 2 |
Neutropenia | D009503 | — | D70 | — | 2 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Plasma cell neoplasms | D054219 | — | — | 2 | — | — | — | — | 2 |
Renal cell carcinoma | D002292 | EFO_0000376 | — | 1 | — | — | — | — | 1 |
Melanoma | D008545 | — | — | 1 | — | — | — | — | 1 |
Retinoblastoma | D012175 | — | — | 1 | — | — | — | — | 1 |
Chordoma | D002817 | EFO_0000334 | — | 1 | — | — | — | — | 1 |
Acute radiation syndrome | D054508 | — | — | 1 | — | — | — | — | 1 |
Fanconi anemia | D005199 | Orphanet_84 | D61.09 | 1 | — | — | — | — | 1 |
Myeloproliferative disorders | D009196 | — | D47.1 | 1 | — | — | — | — | 1 |
Precancerous conditions | D011230 | — | — | 1 | — | — | — | — | 1 |
Drug common name | Amifostine |
INN | amifostine |
Description | Amifostine is an organic thiophosphate that is the S-phospho derivative of 2-[(3-aminopropyl)amino]ethanethiol. A prodrug for the free thiol, WR-1065, which is used as a cytoprotectant in cancer chemotherapy and radiotherapy. It has a role as a prodrug, a radiation protective agent and an antioxidant. It is a diamine and an organic thiophosphate. It is functionally related to a cysteamine. |
Classification | Small molecule |
Drug class | phosphoro-derivatives |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | NCCCNCCSP(=O)(O)O |
PDB | — |
CAS-ID | 20537-88-6 |
RxCUI | 1545987 |
ChEMBL ID | CHEMBL1006 |
ChEBI ID | 2636 |
PubChem CID | 2141 |
DrugBank | DB01143 |
UNII ID | ILA426L95O (ChemIDplus, GSRS) |