Altretamine
Hexalen (altretamine) is a small molecule pharmaceutical. Altretamine was first approved as Hexalen on 1990-12-26. It is used to treat ovarian neoplasms in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| neoplasms | D009369 |
| urogenital diseases | D000091642 |
| endocrine system diseases | D004700 |
Trade Name
FDA
EMA
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| ovarian neoplasms | EFO_0003893 | D010051 | C56 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
120 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ischemia | D007511 | EFO_0000556 | — | 2 | 4 | — | 2 | — | 6 |
| Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | 2 | 2 | — | 1 | — | 4 |
| Peripheral arterial disease | D058729 | EFO_0004265 | — | — | 1 | — | 1 | — | 2 |
| Chronic limb-threatening ischemia | D000089802 | — | — | — | — | — | 2 | — | 2 |
| Vitamin d deficiency | D014808 | EFO_0003762 | E55 | — | — | — | 1 | — | 1 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | 1 | — | 1 |
| Burns | D002056 | — | T30.0 | — | — | — | 1 | — | 1 |
| Cardiopulmonary bypass | D002315 | — | — | — | — | — | 1 | — | 1 |
| Cardiac surgical procedures | D006348 | — | — | — | — | — | 1 | — | 1 |
| Peripheral vascular diseases | D016491 | EFO_0003875 | I73.9 | — | — | — | 1 | — | 1 |
Show 1 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Carcinoma | D002277 | — | C80.0 | 6 | 6 | 1 | — | — | 11 |
| Infections | D007239 | EFO_0000544 | — | 3 | 2 | 1 | — | — | 5 |
| Communicable diseases | D003141 | — | — | 2 | 1 | 1 | — | — | 4 |
| Urologic neoplasms | D014571 | — | C64-C68 | — | 3 | 1 | — | — | 3 |
| Cytomegalovirus infections | D003586 | EFO_0001062 | B25 | 2 | — | 1 | — | — | 3 |
| Urinary bladder neoplasms | D001749 | — | C67 | 2 | 1 | 1 | — | — | 3 |
| Healthy volunteers/patients | — | — | — | 2 | — | 1 | — | — | 3 |
| Chickenpox | D002644 | EFO_0007204 | B01 | — | 2 | 1 | — | — | 3 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 1 | — | 1 | — | — | 2 |
| Virus diseases | D014777 | — | B34 | — | 1 | 1 | — | — | 2 |
Show 6 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 6 | 1 | — | — | 1 | 7 |
| Colorectal neoplasms | D015179 | — | — | 1 | 2 | — | — | 3 | 5 |
| Left ventricular dysfunction | D018487 | — | — | 2 | 5 | — | — | — | 5 |
| Ventricular dysfunction | D018754 | — | — | 2 | 5 | — | — | — | 5 |
| Squamous cell carcinoma of head and neck | D000077195 | — | — | 3 | 2 | — | — | — | 4 |
| Recurrence | D012008 | — | — | 2 | 2 | — | — | — | 4 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 2 | 2 | — | — | — | 3 |
| Non-small-cell lung carcinoma | D002289 | — | — | 2 | 2 | — | — | — | 3 |
| Leukemia | D007938 | — | C95 | 2 | 2 | — | — | — | 3 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 2 | 2 | — | — | — | 3 |
Show 63 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Malaria | D008288 | EFO_0001068 | B54 | 4 | — | — | — | — | 4 |
| Fibrosis | D005355 | — | — | 2 | — | — | — | 1 | 3 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 2 | — | — | — | 1 | 3 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 2 | — | — | — | — | 2 |
| Melanoma | D008545 | — | — | 1 | — | — | — | 1 | 2 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | — | — | — | — | 1 |
| Cholangiocarcinoma | D018281 | — | C22.1 | 1 | — | — | — | — | 1 |
| Gallbladder neoplasms | D005706 | EFO_0004606 | C23 | 1 | — | — | — | — | 1 |
| Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | 1 | — | — | — | — | 1 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 1 | — | — | — | — | 1 |
Show 41 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infertility | D007246 | HP_0000789 | — | — | — | — | — | 7 | 7 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 2 | 2 |
| Subarachnoid hemorrhage | D013345 | EFO_0000713 | I60 | — | — | — | — | 2 | 2 |
| Female infertility | D007247 | EFO_0008560 | N97 | — | — | — | — | 2 | 2 |
| In vitro oocyte maturation techniques | D059471 | — | — | — | — | — | — | 1 | 1 |
| Intracytoplasmic sperm injections | D020554 | — | — | — | — | — | — | 1 | 1 |
| Growth disorders | D006130 | — | — | — | — | — | — | 1 | 1 |
| Humans | D006801 | — | — | — | — | — | — | 1 | 1 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 1 | 1 |
| Stroke | D020521 | EFO_0000712 | I63.9 | — | — | — | — | 1 | 1 |
Show 22 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Altretamine |
| INN | altretamine |
| Description | Hexamethylmelamine is a triamino-1,3,5-triazine. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CN(C)c1nc(N(C)C)nc(N(C)C)n1 |
Identifiers
| PDB | — |
| CAS-ID | 645-05-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1455 |
| ChEBI ID | 24564 |
| PubChem CID | 2123 |
| DrugBank | DB00488 |
| UNII ID | Q8BIH59O7H (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 513 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
19 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use