Lopurin, Duzallo(allopurinol)
Allopurinol, Aloprim, Duzallo, Lopurin, Zyloprim (allopurinol) is a small molecule pharmaceutical. Allopurinol was first approved as Lopurin on 1982-01-01. It is used to treat gout in the USA. It has been approved in Europe to treat gout. The pharmaceutical is active against xanthine dehydrogenase/oxidase.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Trade Name
FDA
EMA
Allopurinol, Aloprim, Lopurin, Zyloprim (discontinued: Allopurinol, Lopurin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Allopurinol sodium
Tradename
Company
Number
Date
Products
ALOPRIMMylanN-020298 RX1996-05-17
1 products, RLD, RS
Allopurinol
Tradename
Company
Number
Date
Products
ZYLOPRIMCasper PharmaN-016084 RX1982-01-01
3 products, RLD
ALLOPURINOLAllerganN-018832 RX1984-09-28
1 products
ALLOPURINOLAllerganN-018877 RX1984-09-28
1 products
Show 3 discontinued
Allopurinol
+
Lesinurad
Tradename
Company
Number
Date
Products
DUZALLOIronwood PharmaceuticalsN-209203 DISCN2017-08-18
2 products, RLD
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
allopurinolANDA2025-03-05
allopurinol sodiumANDA2022-03-01
aloprimNew Drug Application2022-02-18
zyloprimANDA2018-02-24
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
goutEFO_0004274D006073M10
hyperuricemia—D033461—
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Allopurinol / Lesinurad, Duzallo, Ironwood Pharms Inc
85464362032-02-29DP
99562052031-12-28U-2104
92161792031-08-01U-2104
83577132029-12-22DPU-2104
80844832029-08-17U-2104
85464372029-04-29U-2104
82833692028-11-26U-2104
101830122028-11-26U-2104
80036812025-08-25DP
ATC Codes
M: Musculo-skeletal system drugs
— M04: Antigout preparations
— M04A: Antigout preparations
— M04AA: Preparations inhibiting uric acid production
— M04AA01: Allopurinol
— M04AA51: Allopurinol, combinations
HCPCS
No data
Clinical
Clinical Trials
215 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic renal insufficiencyD051436—N18———1—1
Kidney diseasesD007674EFO_0003086N08———1—1
GoutD006073EFO_0004274M10———1—1
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameAllopurinol
INNallopurinol
Description
Allopurinol is a bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring. It has a role as a radical scavenger, a gout suppressant, an antimetabolite and an EC 1.17.3.2 (xanthine oxidase) inhibitor. It is an organic heterobicyclic compound and a nucleobase analogue. It derives from a hydride of a 1H-pyrazolo[4,3-d]pyrimidine.
...
More
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Oc1ncnc2[nH]ncc12
Identifiers
PDB—
CAS-ID315-30-0
RxCUI—
ChEMBL IDCHEMBL1467
ChEBI ID40279
PubChem CID135401907
DrugBankDB00437
UNII ID63CZ7GJN5I (ChemIDplus, GSRS)
Target
Agency Approved
XDH
XDH
Organism
Homo sapiens
Gene name
XDH
Gene synonyms
XDHA
NCBI Gene ID
Protein name
xanthine dehydrogenase/oxidase
Protein synonyms
xanthine oxidoreductase
Uniprot ID
Mouse ortholog
Xdh (22436)
xanthine dehydrogenase/oxidase (Q00519)
Alternate
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
No data
Estimated US medical usage
Allopurinol
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 20,053 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
25,071 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use