Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
nutritional and metabolic diseases | D009750 |
Tradename | Proper name | Company | Number | Date | Products |
---|---|---|---|---|---|
Praluent | alirocumab | Regeneron Pharmaceuticals | N-125559 RX | 2015-07-24 | 2 products |
Brand Name | Status | Last Update |
---|---|---|
praluent | Biologic Licensing Application | 2024-09-03 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
hypercholesterolemia | — | D006937 | — |
atherosclerosis | EFO_0003914 | D050197 | I25.1 |
Expiration | Code | ||
---|---|---|---|
alirocumab, Praluent, Regeneron Pharmaceuticals, Inc. | |||
2028-04-01 | Orphan excl. |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hypercholesterolemia | D006937 | — | — | 10 | 8 | 25 | 4 | 1 | 48 |
Hyperlipoproteinemia type ii | D006938 | EFO_0004911 | E78.00 | — | 3 | 8 | 1 | — | 12 |
Atherosclerosis | D050197 | EFO_0003914 | I25.1 | 1 | — | 1 | 2 | — | 4 |
Dyslipidemias | D050171 | — | — | — | 1 | — | 2 | — | 3 |
Atherosclerotic plaque | D058226 | HP_0031678 | I70 | — | — | 1 | 2 | — | 3 |
Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | — | 2 | — | 2 |
Infarction | D007238 | EFO_0009463 | — | — | — | — | 2 | — | 2 |
Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | — | — | 1 | 1 | — | 2 |
Syndrome | D013577 | — | — | — | 1 | — | 1 | — | 2 |
Acute coronary syndrome | D054058 | EFO_0005672 | — | — | — | 1 | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Homozygous familial hypercholesterolemia | D000090542 | — | — | — | — | 2 | — | — | 2 |
Peritoneal dialysis | D010530 | — | — | — | — | 1 | — | — | 1 |
Carotid artery diseases | D002340 | EFO_0003781 | — | — | — | 1 | — | — | 1 |
Renal dialysis | D006435 | EFO_0010690 | Z99.2 | — | — | 1 | — | — | 1 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | 1 | — | — | 1 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | 1 | — | — | 1 |
Coronary circulation | D003326 | — | — | — | — | 1 | — | — | 1 |
Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Non-small-cell lung carcinoma | D002289 | — | — | — | 2 | — | — | — | 2 |
Lung neoplasms | D008175 | — | C34.90 | — | 2 | — | — | — | 2 |
Nephrotic syndrome | D009404 | EFO_0004255 | N04 | — | 1 | — | — | — | 1 |
Nephrosis | D009401 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
Hemorrhage | D006470 | MP_0001914 | R58 | 1 | — | — | — | — | 1 |
Stroke | D020521 | EFO_0000712 | I63.9 | 1 | — | — | — | — | 1 |
Intracranial arteriosclerosis | D002537 | EFO_1000860 | I67.2 | 1 | — | — | — | — | 1 |
Sepsis | D018805 | EFO_0001420 | A41.9 | 1 | — | — | — | — | 1 |
Toxemia | D014115 | — | — | 1 | — | — | — | — | 1 |
Drug common name | Alirocumab |
INN | alirocumab |
Description | Alirocumab (human mab) |
Classification | Antibody |
Drug class | monoclonal antibodies |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL2109540 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB09302 |
UNII ID | PP0SHH6V16 (ChemIDplus, GSRS) |