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Drug ReportsAlclometasone
ALCLOMETASONE DIPROPIONATE
Alclometasone (alclometasone dipropionate) is a small molecule pharmaceutical. Alclometasone dipropionate was first approved as Aclovate on 1982-12-14. It is used to treat dermatitis, facial dermatoses, foot dermatoses, hand dermatoses, and inflammation amongst others in the USA.
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Financial
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Alclometasone (discontinued: Aclovate)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Alclometasone dipropionate
Tradename
Company
Number
Date
Products
ACLOVATEFougera PharmaceuticalsN-018707 DISCN1982-12-14
1 products, RLD
ACLOVATEFougera PharmaceuticalsN-018702 DISCN1982-12-14
1 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
alclometasone dipropionateANDA2021-04-05
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
D07: Corticosteroids, dermatological preparations
D07A: Corticosteroid dermatological preparations, plain
D07AB: Corticosteroids, moderately potent (group ii)
D07AB10: Alclometasone
S: Sensory organ drugs
S01: Ophthalmologicals
S01B: Antiinflammatory agents, ophthalmologic
S01BA: Corticosteroid ophthalmologic antiinflammatory agents, plain
S01BA10: Alclometasone
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD00228911
Lung neoplasmsD008175HP_0100526C34.9011
PsoriasisD011565EFO_0000676L4011
EczemaD004485HP_0000964L30.911
PruritusD011537HP_0000989L2911
HypersensitivityD006967HP_0012393T78.4011
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameALCLOMETASONE DIPROPIONATE
INNalclometasone
Description
Alclometasone dipropionate is a prednisolone compound having an alpha-chloro substituent at the 7-position, an alpha-methyl substituent at the 16-position and O-propanoyl groups at the 17- and 21-positions. It has a role as an anti-inflammatory drug. It is a 20-oxo steroid, an 11beta-hydroxy steroid, a glucocorticoid, a steroid ester, a propanoate ester, a 3-oxo-Delta(1),Delta(4)-steroid and a chlorinated steroid. It is functionally related to a prednisolone.
Classification
Small molecule
Drug classCorticosteroid; Glucocorticoid
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Structure (InChI/SMILES or Protein Sequence)
CCC(=O)OCC(=O)[C@@]1(OC(=O)CC)[C@H](C)C[C@H]2[C@H]3[C@H]([C@@H](O)C[C@@]21C)[C@@]1(C)C=CC(=O)C=C1C[C@H]3Cl
Identifiers
PDB
CAS-ID66734-13-2
RxCUI
ChEMBL IDCHEMBL1200989
ChEBI ID31184
PubChem CID636374
DrugBankDB00240
UNII ID136H45TB7B (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
No data
Estimated US medical usage
Alclometasone dipropionate
+
Alclometasone
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 149 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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117 adverse events reported
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