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Drug ReportsAlcaftadine
Alcaftadine
Alcaftadine, Lastacaft (alcaftadine) is a small molecule pharmaceutical. Alcaftadine was first approved as Lastacaft on 2010-07-28. It is used to treat allergic conjunctivitis in the USA.
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Drug
Target
Variants
Financial
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Safety
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5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
eye diseasesD005128
immune system diseasesD007154
Trade Name
FDA
EMA
Alcaftadine, Lastacaft (discontinued: Alcaftadine)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Alcaftadine
Tradename
Company
Number
Date
Products
LASTACAFTAbbVieN-022134 OTC2010-07-28
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
alcaftadineANDA2024-10-07
lastacaftNew Drug Application2022-08-10
Indications
FDA
EMA
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Alcaftadine, Lastacaft, Abbvie
86642152027-12-23U-3267
106176952027-03-19DPU-3267
ATC Codes
S: Sensory organ drugs
S01: Ophthalmologicals
S01G: Decongestants and antiallergics
S01GX: Other antiallergics in atc
S01GX11: Alcaftadine
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ConjunctivitisD003231HP_0000509H1055212
Allergic conjunctivitisD003233EFO_0007141H10.4455212
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameAlcaftadine
INNalcaftadine
Description
Alcaftadine is an imidazobenzazepine that is 6,11-dihydro-5H-imidazo[2,1-b][3]benzazepine substituted at position 3 by a formyl group and at position 11 by a 1-methylpiperidin-4-ylidene group. An antihistamine used for treatment of allergic conjunctivitis. It has a role as a H1-receptor antagonist and an anti-allergic agent. It is an aldehyde, a member of piperidines, an imidazobenzazepine and a tertiary amino compound.
Classification
Small molecule
Drug class
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Structure (InChI/SMILES or Protein Sequence)
CN1CCC(=C2c3ccccc3CCn3c(C=O)cnc32)CC1
Identifiers
PDB
CAS-ID147084-10-4
RxCUI
ChEMBL IDCHEMBL1201747
ChEBI ID71023
PubChem CID19371515
DrugBankDB06766
UNII ID7Z8O94ECSX (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
No data
Estimated US medical usage
Alcaftadine
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 83 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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682 adverse events reported
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