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AboutPricing
Drug ReportsAlbuterol
Albuterol
Airsupra, Albuterol, Combivent, Proair, Proventil, Proventil-hfa, Ventolin (albuterol) is a small molecule pharmaceutical. Albuterol was first approved as Ventolin on 1982-01-01. It is used to treat asthma and bronchial spasm in the USA. The pharmaceutical is active against beta-2 adrenergic receptor.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
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Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
immune system diseasesD007154
Trade Name
FDA
EMA
Albuterol, Proair, Proventil-hfa, Ventolin (discontinued: Accuneb, Albuterol, Proair, Proventil, Ventolin, Ventolin rotacaps, Volmax, Vospire)
Combinations
Airsupra, Albuterol ipratropium, Combivent (discontinued: Albuterol ipratropium, Combivent, Duoneb)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Albuterol sulfate
Tradename
Company
Number
Date
Products
VENTOLIN HFAGSKN-020983 RX2001-04-19
1 products, RLD, RS
PROVENTIL-HFAKindeva Drug DeliveryN-020503 RX1996-08-15
1 products, RLD, RS
PROAIR HFATevaN-021457 RX2004-10-29
1 products, RLD, RS
PROAIR RESPICLICKTevaN-205636 RX2015-03-31
1 products, RLD, RS
Show 12 discontinued
Albuterol sulfate
+
Ipratropium bromide
Tradename
Company
Number
Date
Products
COMBIVENT RESPIMATBoehringer IngelheimN-021747 RX2011-10-07
1 products, RLD, RS
Show 2 discontinued
Albuterol
Tradename
Company
Number
Date
Products
VENTOLINGSKN-018473 DISCN1982-01-01
1 products
PROVENTILMerck & CoN-017559 DISCN1982-01-01
1 products
Hide discontinued
Albuterol sulfate
+
Budesonide
Tradename
Company
Number
Date
Products
AIRSUPRAAstraZenecaN-214070 RX2023-01-10
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
airsupraNew Drug Application2025-09-18
albuterolANDA2025-04-21
albuterol sulateNDA authorized generic2026-01-30
albuterol sulfateANDA2026-02-16
albuterol sulfate hfaNDA authorized generic2023-02-06
albuterol sulfate inhalationANDA2024-12-20
albuterol sulfate inhalation solutionANDA2025-12-10
albuterol sulfate inhalation solution, 0.5%ANDA2025-12-10
basic dental emergency kitunapproved drug other2025-10-16
combivent respimatNew Drug Application2025-12-01
Show 14 more
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
asthmaEFO_0000270D001249J45
bronchial spasm—D001986—
bronchitis—D001991J40
allergic rhinitis perennialEFO_1001417D012221J30.89
pulmonary emphysema—D011656J43
vasomotor rhinitisEFO_0007533D012223J30.0
inflammatory bowel diseasesEFO_0003767D015212—
Agency Specific
FDA
EMA
Expiration
Code
ALBUTEROL SULFATE / BUDESONIDE, AIRSUPRA, ASTRAZENECA
2026-01-10NP
Patent Expiration
Patent
Expires
Flag
FDA Information
Albuterol Sulfate, Proair Digihaler, Teva Branded Pharm
112667962041-02-22DP
111732592040-07-06DP
114649232040-06-19DP
114397772040-05-24DP
113446852039-09-26DP
110006532038-12-18DP
113579352038-09-24DP
113513172038-02-10DP
105690342036-08-16DP
109188162035-12-14DP
97825502035-08-28DP
97825512035-08-28DP
89789662032-01-13DP
92162602031-06-28DP
97310872031-05-18DP
100225102031-05-18DP
101241312031-05-18DP
86511032028-03-26DP
94632882025-05-19DP
107658202025-05-19DP
Albuterol Sulfate, Proair Hfa, Teva Branded Pharm
105618082032-01-01DP
94632892031-05-18DP
98085872031-05-18DP
100225092031-05-18DP
100861562031-05-18DP
106955122031-05-18DP
113958892031-05-18DP
81327122028-09-07DP
Albuterol Sulfate / Ipratropium Bromide, Combivent Respimat, Boehringer Ingelheim
87333412030-10-16DP
78372352028-03-13DP
90279672027-03-31DP
73963412026-10-10DP
Albuterol Sulfate / Budesonide, Airsupra, Astrazeneca
94150092030-05-28U-3509
ATC Codes
R: Respiratory system drugs
— R03: Drugs for obstructive airway diseases
— R03A: Adrenergics, inhalants
— R03AC: Selective beta-2-adrenoreceptor agonist inhalants
— R03AC02: Salbutamol
— R03AK: Adrenergics inhalants in combination with corticosteroids or other drugs, excl. anticholinergics
— R03AK04: Salbutamol and sodium cromoglicate
— R03AK13: Salbutamol and beclometasone
— R03AL: Adrenergics in combination with anticholinergics incl. triple combinations with corticosteroids
— R03AL02: Salbutamol and ipratropium bromide
— R03C: Adrenergics for systemic use
— R03CC: Selective beta-2-adrenoreceptor agonists, systemic
— R03CC02: Salbutamol
HCPCS
Code
Description
J7607
Levalbuterol, inhalation solution, compounded product, administered through dme, concentrated form, 0.5 mg
J7609
Albuterol, inhalation solution, compounded product, administered through dme, unit dose, 1 mg
J7610
Albuterol, inhalation solution, compounded product, administered through dme, concentrated form, 1 mg
J7611
Albuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, concentrated form, 1 mg
J7612
Levalbuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, concentrated form, 0.5 mg
J7613
Albuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose, 1 mg
J7614
Levalbuterol, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose, 0.5 mg
J7615
Levalbuterol, inhalation solution, compounded product, administered through dme, unit dose, 0.5 mg
J7620
Albuterol, up to 2.5 mg and ipratropium bromide, up to 0.5 mg, fda-approved final product, non-compounded, administered through dme
Clinical
Clinical Trials
943 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J45347212611399441
Chronic obstructive pulmonary diseaseD029424EFO_0000341J44.91335857764272
Obstructive lung diseasesD008173——626584337168
Lung diseasesD008171EFO_0003818J98.4524684128165
Respiratory aspirationD053120EFO_1001839—142154439
Healthy volunteers/patients———191—31538
BronchiolitisD001988——34151326
Status asthmaticusD013224——2544618
Bronchial spasmD001986———254314
Exercise-induced asthmaD001250—J45.990——64111
Show 62 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cystic fibrosisD003550EFO_0000390E84——2—1113
Respiratory distress syndromeD012128EFO_1000637J80242—17
Respiratory tract diseasesD012140———11—24
Respiration disordersD012120—J00-J99——1—34
Acute lung injuryD055371EFO_0004610—121—14
Bronchial hyperreactivityD016535————1—34
Transient tachypnea of the newbornD059245—P22.12—1——3
Retinopathy of prematurityD012178EFO_1001158H35.1—21——2
Wounds and injuriesD014947—T14.8—11—12
ConjunctivitisD003231—H10——2——2
Show 13 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CoughD003371—R05—1——12
Pulmonary hypertensionD006976EFO_0001361I27.2011———2
SclerosisD012598———1——12
LymphangioleiomyomatosisD018192—J84.8111———1
Viral bronchiolitisD001990———1———1
Brain deathD001926—G93.82—1———1
Pulmonary edemaD011654EFO_1001134J81—1———1
Amyotrophic lateral sclerosisD000690EFO_0000253G12.21—1———1
Motor neuron diseaseD016472EFO_0003782G12.2—1———1
Altitude sicknessD000532EFO_1000782T70.2911———1
Show 1 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Therapeutic equivalencyD013810——14————14
FibrosisD005355——1———89
Covid-19D000086382—U07.11———45
Cardiovascular diseasesD002318EFO_0000319I981———34
Diabetes mellitusD003920EFO_0000400E08-E132———13
Ciliary motility disordersD002925EFO_0003900—1———23
Sickle cell anemiaD000755EFO_0000697D571———12
TachypneaD059246—R06.822————2
Major depressive disorderD003865EFO_0003761F221————1
CicatrixD002921—L90.51————1
Show 6 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SmokingD012907EFO_0004318—————44
Airway remodelingD056151——————33
InfectionsD007239EFO_0000544—————33
Respiratory signs and symptomsD012818——————22
Lung neoplasmsD008175—C34.90————22
Muscular dystrophiesD009136EFO_0000757G71.0————22
Child mortalityD046688——————22
Noninvasive ventilationD063087——————22
Artificial respirationD012121——————11
Pulmonary atelectasisD001261—J98.1————11
Show 70 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameAlbuterol
INNsalbutamol
Description
Albuterol is a member of the class of phenylethanolamines that is 4-(2-amino-1-hydroxyethyl)-2-(hydroxymethyl)phenol having a tert-butyl group attached to the nirogen atom. It acts as a beta-adrenergic agonist used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It has a role as a bronchodilator agent, a beta-adrenergic agonist, an environmental contaminant and a xenobiotic. It is a member of phenylethanolamines, a secondary amino compound and a member of phenols.
Classification
Small molecule
Drug classbronchodilators (phenethylamine derivatives)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC(C)(C)NCC(O)c1ccc(O)c(CO)c1
Identifiers
PDB—
CAS-ID18559-94-9
RxCUI—
ChEMBL IDCHEMBL714
ChEBI ID2549
PubChem CID2083
DrugBankDB01001
UNII IDQF8SVZ843E (ChemIDplus, GSRS)
Target
Agency Approved
ADRB2
ADRB2
Organism
Homo sapiens
Gene name
ADRB2
Gene synonyms
ADRB2R, B2AR
NCBI Gene ID
154
Protein name
beta-2 adrenergic receptor
Protein synonyms
adrenergic, beta-2-, receptor, surface, adrenoceptor beta 2 surface, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, catecholamine receptor
Uniprot ID
Q9UMZ5
Mouse ortholog
Adrb2 (11555)
beta-2 adrenergic receptor (Q8BH38)
Alternate
No data
Variants
No data
Financial
Revenue by drug
$
€
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Airsupra – AstraZeneca
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Proair – Teva
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Estimated US medical usage
Albuterol
Total medical expenditures per year (USD, in millions)
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Albuterol
+
Ipratropium
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 9,999 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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136,004 adverse events reported
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