Albendazole
Albendazole (albendazole) is a small molecule pharmaceutical. Albendazole was first approved as Albenza on 1996-06-11. It is used to treat ancylostomiasis, clonorchiasis, echinococcosis, enterobiasis, and giardiasis amongst others in the USA.
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Albendazole
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| ALBENZA | Impax Laboratories | N-020666 DISCN | 1996-06-11 | 1 products, RLD |
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EMA
Brand Name | Status | Last Update |
|---|---|---|
| albendazole | ANDA | 2024-01-16 |
| albenza | New Drug Application | 2019-09-25 |
| antiseptic skin cleanser | New Drug Application | 2024-02-13 |
| rugby petrolatum hydrating | C200263 | 2024-02-12 |
| zentel | unapproved drug other | 2019-03-18 |
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137 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Filarial elephantiasis | D004605 | EFO_0007272 | B74.0 | — | 6 | 3 | 4 | 10 | 22 |
| Helminthiasis | D006373 | EFO_1001342 | B65-B83 | 2 | 3 | 2 | 4 | 9 | 19 |
| Trichuriasis | D014257 | EFO_0007524 | B79 | — | 9 | 5 | 2 | 1 | 15 |
| Hookworm infections | D006725 | EFO_0007314 | B76 | — | 6 | 3 | 1 | 1 | 10 |
| Infections | D007239 | EFO_0000544 | — | — | 2 | 2 | 3 | 4 | 9 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | — | 2 | 1 | 5 | 8 |
| Malaria | D008288 | EFO_0001068 | B54 | — | 1 | 2 | 1 | 5 | 8 |
| Ascariasis | D001196 | EFO_0007154 | B77 | — | 2 | 3 | 1 | 2 | 7 |
| Anemia | D000740 | HP_0001903 | D64.9 | — | 1 | 1 | 3 | 3 | 7 |
| Trachoma | D014141 | — | A71 | — | — | 1 | 2 | — | 3 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Onchocerciasis | D009855 | EFO_0007402 | B73 | — | 3 | 3 | — | 2 | 8 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | — | 2 | — | 4 | 6 |
| Neurocysticercosis | D020019 | — | — | — | 2 | 5 | — | — | 6 |
| Strongyloidiasis | D013322 | EFO_0007501 | B78 | — | — | 2 | — | 1 | 3 |
| Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | — | 1 | — | 2 | 3 |
| Healthy volunteers/patients | — | — | — | 1 | 1 | 1 | — | — | 3 |
| Yaws | D015001 | EFO_0007548 | A66 | — | 1 | 1 | — | — | 2 |
| Scabies | D012532 | — | B86 | — | — | 1 | — | 1 | 2 |
| Epilepsy | D004827 | EFO_0000474 | G40.9 | — | 1 | 1 | — | 1 | 2 |
| Hiv | D006678 | — | O98.7 | — | — | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Wounds and injuries | D014947 | — | T14.8 | — | 1 | — | — | — | 1 |
| Neoplasms | D009369 | — | C80 | — | 1 | — | — | — | 1 |
| Typhoid fever | D014435 | EFO_0006789 | A01.0 | 1 | 1 | — | — | — | 1 |
| Cholera | D002771 | — | A00 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pharmacokinetics | D010599 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Parasitic diseases | D010272 | EFO_0001067 | B88 | — | — | — | — | 5 | 5 |
| Abdominal pain | D015746 | HP_0002027 | R10.9 | — | — | — | — | 2 | 2 |
| Growth disorders | D006130 | — | — | — | — | — | — | 1 | 1 |
| Nutrition disorders | D009748 | EFO_0001069 | — | — | — | — | — | 1 | 1 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 1 | 1 |
| Bacterial infections | D001424 | — | A49 | — | — | — | — | 1 | 1 |
| Cysticercosis | D003551 | EFO_0007231 | B69 | — | — | — | — | 1 | 1 |
| Impetigo | D007169 | EFO_1000714 | L01 | — | — | — | — | 1 | 1 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Albendazole |
| INN | albendazole |
| Description | Albendazole is a carbamate ester that is methyl 1H-benzimidazol-2-ylcarbamate substituted by a propylsulfanyl group at position 5. It is commonly used in the treatment of parasitic worm infestations. It has a role as a tubulin modulator, a microtubule-destabilising agent and an anthelminthic drug. It is a carbamate ester, a benzimidazolylcarbamate fungicide, an aryl sulfide and a member of benzimidazoles. |
| Classification | Small molecule |
| Drug class | antithelmintics (tibendazole type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCSc1ccc2[nH]c(NC(=O)OC)nc2c1 |
Identifiers
| PDB | — |
| CAS-ID | 54965-21-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1483 |
| ChEBI ID | 16664 |
| PubChem CID | 2082 |
| DrugBank | DB00518 |
| UNII ID | F4216019LN (ChemIDplus, GSRS) |
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Albendazole
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1,266 adverse events reported
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