Tradename | Company | Number | Date | Products |
---|---|---|---|---|
SCENESSE | Clinuvel Pharmaceuticals | N-210797 RX | 2019-10-08 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
scenesse | New Drug Application | 2024-08-14 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
erythropoietic protoporphyria | — | D046351 | E80.0 |
Expiration | Code | ||
---|---|---|---|
AFAMELANOTIDE, SCENESSE, CLIVUNEL INC | |||
2026-10-08 | ODE-270 | ||
2024-10-08 | NCE |
Code | Description |
---|---|
J7352 | Afamelanotide implant, 1 mg |
Drug common name | Afamelanotide |
INN | afamelanotide |
Description | Afamelanotide is a polypeptide comprising of 13 amino acids which is an analogue of alpha-melanocyte stimulating hormone. It is approved as a dermatologic drug for the prevention of phototoxicity in adult patients with erythropoietic protoporphyria. It has a role as a dermatologic drug. |
Classification | Protein |
Drug class | peptides: melanocortin receptor agonists |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | CCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(C)=O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@H](C(N)=O)C(C)C |
PDB | — |
CAS-ID | 75921-69-6 |
RxCUI | — |
ChEMBL ID | CHEMBL441738 |
ChEBI ID | — |
PubChem CID | 16154396 |
DrugBank | DB04931 |
UNII ID | QW68W3J66U (ChemIDplus, GSRS) |