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Drug ReportsAcoramidis
Acoramidis
Acoramidis is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AmyloidosisD000686EFO_1001875E85167
CardiomyopathiesD009202EFO_0000318I421247
PolyneuropathiesD011115EFO_0009562A69.2233
Familial amyloid neuropathiesD028227E85.133
Amyloid neuropathiesD01777222
Heart diseasesD006331EFO_0003777I51.922
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Covid-19D00008638211
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients11
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameAcoramidis
INNacoramidis
Description
Acoramidis (AG10) is an investigational transthyretin stabilizer developed to treat transthyretin amyloid cardiomyopathy. It is delivered by mouth. An alternative treatment is tafamidis.
Classification
Small molecule
Drug classantimyloidotics
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Structure (InChI/SMILES or Protein Sequence)
Cc1n[nH]c(C)c1CCCOc1cc(C(=O)O)ccc1F
Identifiers
PDB
CAS-ID1446711-81-4
RxCUI
ChEMBL IDCHEMBL3940890
ChEBI ID
PubChem CID71464713
DrugBank
UNII IDT12B44A1OE (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 515 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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12 adverse events reported
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