Acoramidis
Acoramidis is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Amyloidosis | D000686 | EFO_1001875 | E85 | 1 | — | 6 | — | — | 7 |
| Cardiomyopathies | D009202 | EFO_0000318 | I42 | 1 | 2 | 4 | — | — | 7 |
| Polyneuropathies | D011115 | EFO_0009562 | A69.22 | — | — | 3 | — | — | 3 |
| Familial amyloid neuropathies | D028227 | — | E85.1 | — | — | 3 | — | — | 3 |
| Amyloid neuropathies | D017772 | — | — | — | — | 2 | — | — | 2 |
| Heart diseases | D006331 | EFO_0003777 | I51.9 | — | — | 2 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Acoramidis |
| INN | acoramidis |
| Description | Acoramidis (AG10) is an investigational transthyretin stabilizer developed to treat transthyretin amyloid cardiomyopathy. It is delivered by mouth. An alternative treatment is tafamidis.
|
| Classification | Small molecule |
| Drug class | antimyloidotics |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1n[nH]c(C)c1CCCOc1cc(C(=O)O)ccc1F |
Identifiers
| PDB | — |
| CAS-ID | 1446711-81-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3940890 |
| ChEBI ID | — |
| PubChem CID | 71464713 |
| DrugBank | — |
| UNII ID | T12B44A1OE (ChemIDplus, GSRS) |
Target
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Financial
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Trends
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Safety
Black-box Warning
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Adverse Events
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12 adverse events reported
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