Acetyldigitoxin
Acylanid (acetyldigitoxin) is a small molecule pharmaceutical. Acetyldigitoxin was first approved as Acylanid on 1982-01-01. The pharmaceutical is active against sodium/potassium-transporting ATPase subunit alpha-1.
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Drug
General
| Drug common name | Acetyldigitoxin |
| INN | acetyldigitoxin |
| Description | Acetyldigitoxin is a cardiac glycoside. It is an acetyl derivative of digitoxin, found in the leaves of Digitalis species. It is used to treat cardiac failure, particularly that associated with tachycardia.
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| Classification | Small molecule |
| Drug class | fluoroquinolone derivatives, nonantibacterial indication (e.g., antineoplastic antibiotics) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)O[C@H]1C[C@H](O[C@H]2[C@@H](O)C[C@H](O[C@H]3[C@@H](O)C[C@H](O[C@H]4CC[C@]5(C)[C@H]6CC[C@]7(C)[C@@H](C8=CC(=O)OC8)CC[C@]7(O)[C@@H]6CC[C@@H]5C4)O[C@@H]3C)O[C@@H]2C)O[C@H](C)[C@H]1O |
Identifiers
| PDB | — |
| CAS-ID | 7263-26-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3545057 |
| ChEBI ID | 53773 |
| PubChem CID | 68949 |
| DrugBank | DB00511 |
| UNII ID | 0ZV4Q4L2FU (ChemIDplus, GSRS) |
Target
Agency Approved
ATP1A1
ATP1A1
Organism
Homo sapiens
Gene name
ATP1A1
Gene synonyms
NCBI Gene ID
Protein name
sodium/potassium-transporting ATPase subunit alpha-1
Protein synonyms
ATPase, Na+/K+ transporting, alpha 1 polypeptide, Na(+)/K(+) ATPase alpha-1 subunit, Na+/K+ ATPase 1, Na, K-ATPase, alpha-A catalytic polypeptide, Na,K-ATPase alpha-1 subunit, Na,K-ATPase catalytic subunit alpha-A protein, Sodium pump subunit alpha-1, sodium-potassium ATPase catalytic subunit alpha-1, sodium-potassium-ATPase, alpha 1 polypeptide
Uniprot ID
Mouse ortholog
Atp1a1 (11928)
sodium/potassium-transporting ATPase subunit alpha-1 (Q91Z09)
Alternate
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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