Acetylcarnitine
Acetylcarnitine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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2Y
5Y
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FDA approval date
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Patent expiration date
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Last update post date
Start date
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| nutritional and metabolic diseases | D009750 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
66 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fatigue | D005221 | — | R53.83 | — | 1 | 3 | 1 | 1 | 6 |
| Cognitive dysfunction | D060825 | — | G31.84 | — | 2 | — | 1 | — | 3 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 1 | — | 1 | — | 2 |
| Nervous system diseases | D009422 | — | G00-G99 | — | — | — | 1 | 1 | 2 |
| Chronic hepatitis c | D019698 | EFO_0004220 | B18.2 | — | — | — | 1 | — | 1 |
| Hepatitis | D006505 | — | K75.9 | — | — | — | 1 | — | 1 |
| Hepatitis a | D006506 | EFO_0007305 | B15 | — | — | — | 1 | — | 1 |
| Poisoning | D011041 | EFO_0008546 | T65.91 | — | — | — | 1 | — | 1 |
| Cerebrovascular disorders | D002561 | EFO_0003763 | I60-I69 | — | — | — | 1 | — | 1 |
| Migraine disorders | D008881 | EFO_0003821 | G43 | — | — | — | 1 | — | 1 |
Show 3 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Peripheral nervous system diseases | D010523 | — | G64 | — | 2 | 3 | — | 1 | 6 |
| Syndrome | D013577 | — | — | — | 2 | 1 | — | 2 | 4 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | 1 | — | 1 | 3 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | 1 | — | — | 2 |
| Carpal tunnel syndrome | D002349 | EFO_0004143 | G56.0 | — | 1 | 1 | — | 1 | 2 |
| Neurotoxicity syndromes | D020258 | — | G92 | — | — | 2 | — | — | 2 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | 1 | — | — | 2 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | 1 | — | — | 1 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | — | 1 | — | — | 1 |
| Occupational stress | D000073397 | — | — | — | — | 1 | — | — | 1 |
Show 17 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infertility | D007246 | EFO_0000545 | — | — | 1 | — | — | 5 | 6 |
| Male infertility | D007248 | EFO_0004248 | N46 | 1 | 1 | — | — | 4 | 5 |
| Brain injuries | D001930 | — | S06.9 | 1 | 1 | — | — | 1 | 2 |
| Chronic fatigue syndrome | D015673 | EFO_0004540 | G93.31 | — | 1 | — | — | 1 | 2 |
| Depression | D003863 | — | F33.9 | — | 1 | — | — | 1 | 2 |
| Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | 1 | 2 |
| Multiple myeloma | D009101 | — | C90.0 | — | 1 | — | — | — | 1 |
| Plasma cell neoplasms | D054219 | — | — | — | 1 | — | — | — | 1 |
| Consciousness disorders | D003244 | — | — | 1 | 1 | — | — | — | 1 |
| Prostatic neoplasms | D011471 | — | C61 | — | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | 1 | — | — | — | — | 1 |
| Chronic progressive multiple sclerosis | D020528 | EFO_0003840 | — | 1 | — | — | — | — | 1 |
| Sclerosis | D012598 | — | — | 1 | — | — | — | — | 1 |
| Pancreatitis | D010195 | EFO_0000278 | K85 | 1 | — | — | — | — | 1 |
| Chronic pancreatitis | D050500 | EFO_0000342 | K86.1 | 1 | — | — | — | — | 1 |
| Alcoholism | D000437 | EFO_0003829 | F10.1 | 1 | — | — | — | — | 1 |
| Alcohol drinking | D000428 | EFO_0004329 | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Brain diseases | D001927 | — | G93.40 | — | — | — | — | 3 | 3 |
| Hepatic encephalopathy | D006501 | — | K72.91 | — | — | — | — | 3 | 3 |
| Healthy volunteers/patients | — | — | — | — | — | — | — | 2 | 2 |
| Humans | D006801 | — | STY/T016 | — | — | — | — | 2 | 2 |
| Culture media | D003470 | — | — | — | — | — | — | 2 | 2 |
| Blastocystis | D016844 | — | — | — | — | — | — | 2 | 2 |
| Embryo research | D033041 | — | — | — | — | — | — | 2 | 2 |
| Autistic disorder | D001321 | EFO_0003758 | F84.0 | — | — | — | — | 1 | 1 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 1 | 1 |
| Insulin resistance | D007333 | EFO_0002614 | E88.819 | — | — | — | — | 1 | 1 |
Show 22 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Acetylcarnitine |
| INN | — |
| Description | O-acetylcarnitine is an O-acylcarnitine having acetyl as the acyl substituent. It has a role as a human metabolite. It is functionally related to an acetic acid. It is a conjugate base of an O-acetylcarnitinium. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)O[C@H](CC(=O)[O-])C[N+](C)(C)C |
Identifiers
| PDB | — |
| CAS-ID | 3040-38-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1697733 |
| ChEBI ID | 57589 |
| PubChem CID | 1 |
| DrugBank | DB08842 |
| UNII ID | — |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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55 adverse events reported
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