Acenocoumarol
Acenocoumarol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target vitamin K epoxide reductase complex subunit 1.
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Drug
Target
Variants
Financial
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Safety
Events Timeline
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
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Indications
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Agency Specific
FDA
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Patent Expiration
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HCPCS
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Clinical
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Drug
General
| Drug common name | Acenocoumarol |
| INN | acenocoumarol |
| Description | Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is generic, so is marketed under many brand names worldwide.
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| Classification | Small molecule |
| Drug class | anticoagulants (dicumarol type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)CC(c1ccc([N+](=O)[O-])cc1)c1c(O)c2ccccc2oc1=O |
Identifiers
| PDB | — |
| CAS-ID | 152-72-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL397420 |
| ChEBI ID | 53766 |
| PubChem CID | 9052 |
| DrugBank | DB01418 |
| UNII ID | I6WP63U32H (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
VKORC1
VKORC1
Organism
Homo sapiens
Gene name
VKORC1
Gene synonyms
VKOR
NCBI Gene ID
Protein name
vitamin K epoxide reductase complex subunit 1
Protein synonyms
phylloquinone epoxide reductase, vitamin K dependent clotting factors deficiency 2, Vitamin K1 2,3-epoxide reductase subunit 1, vitamin K1 epoxide reductase (warfarin-sensitive)
Uniprot ID
Mouse ortholog
Vkorc1 (27973)
vitamin K epoxide reductase complex subunit 1 (Q9CRC0)
Variants
No data
Financial
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Trends
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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