Aceclidine
Aceclidine is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target muscarinic acetylcholine receptor M5, muscarinic acetylcholine receptor M1, muscarinic acetylcholine receptor M3, muscarinic acetylcholine receptor M4, and muscarinic acetylcholine receptor M2.
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6 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Presbyopia | D011305 | — | H52.4 | 1 | 3 | 2 | — | — | 6 |
| Eye diseases | D005128 | EFO_0003966 | H44 | 1 | 2 | 2 | — | — | 5 |
| Refractive errors | D012030 | EFO_0003908 | H52.7 | 1 | 2 | 1 | — | — | 4 |
| Miosis | D015877 | HP_0000616 | H57.03 | — | 1 | 2 | — | — | 3 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Aceclidine |
| INN | aceclidine |
| Description | Acetic acid 1-azabicyclo[2.2.2]octan-3-yl ester is a member of quinuclidines. |
| Classification | Small molecule |
| Drug class | muscarinic receptor agonists/antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)OC1CN2CCC1CC2 |
Identifiers
| PDB | — |
| CAS-ID | 827-61-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL20835 |
| ChEBI ID | — |
| PubChem CID | 1979 |
| DrugBank | — |
| UNII ID | 0578K3ELIO (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
CHRM5
CHRM5
CHRM1
CHRM1
CHRM3
CHRM3
CHRM4
CHRM4
CHRM2
CHRM2
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