Cibinqo(abrocitinib)
Cibinqo (abrocitinib) is a small molecule pharmaceutical. Abrocitinib was first approved as Cibinqo on 2021-12-09. It is used to treat atopic dermatitis in the USA. It has been approved in Europe to treat atopic dermatitis. It is known to target tyrosine-protein kinase JAK2 and tyrosine-protein kinase JAK1.
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Commercial
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Cibinqo
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| cibinqo | New Drug Application | 2025-03-20 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| atopic dermatitis | EFO_0000274 | D003876 | L20 |
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
ABROCITINIB, CIBINQO, PFIZER | |||
| 2027-01-14 | NCE | ||
| 2026-02-09 | NPP | ||
HCPCS
No data
Clinical
No data
Drug
General
| Drug common name | Abrocitinib |
| INN | abrocitinib |
| Description | Abrocitinib, sold under the brand name Cibinqo, is a medication used for the treatment of atopic dermatitis (eczema). It is a Janus kinase inhibitor and it was developed by Pfizer. It is taken by mouth.
|
| Classification | Small molecule |
| Drug class | tyrosine kinase inhibitors: tyrosine kinase inhibitors; janus kinase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCCS(=O)(=O)N[C@H]1C[C@@H](N(C)c2ncnc3[nH]ccc23)C1 |
Identifiers
| PDB | — |
| CAS-ID | 1622902-68-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3655081 |
| ChEBI ID | — |
| PubChem CID | 78323835 |
| DrugBank | DB14973 |
| UNII ID | 73SM5SF3OR (ChemIDplus, GSRS) |
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Cibinqo – Pfizer
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Safety
Black-box Warning
Black-box warning for: Cibinqo
Adverse Events
0 adverse events reported
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