Tradename | Proper name | Company | Number | Date | Products |
---|---|---|---|---|---|
Orencia | abatacept | Bristol-Myers Squibb Company | N-125118 RX | 2005-12-23 | 5 products |
Brand Name | Status | Last Update |
---|---|---|
orencia | Biologic Licensing Application | 2023-10-30 |
Expiration | Code | ||
---|---|---|---|
abatacept, Orencia, Bristol-Myers Squibb Company | |||
2028-12-15 | Orphan excl. |
Code | Description |
---|---|
J0129 | Injection, abatacept, 10 mg (code may be used for medicare when drug administered under the direct supervision of a physician, not for use when drug is self administered) |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 10 | 14 | 33 | 23 | 52 | 128 |
Kidney transplantation | D016030 | — | — | 3 | 8 | 3 | 5 | 3 | 21 |
Psoriatic arthritis | D015535 | EFO_0003778 | L40.5 | — | 1 | 2 | 1 | 4 | 8 |
Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | 2 | 1 | 3 | 1 | 1 | 7 |
Covid-19 | D000086382 | — | U07.1 | 1 | 2 | 1 | 1 | 1 | 5 |
Dermatomyositis | D003882 | EFO_0000398 | M33 | 1 | 1 | 1 | 1 | — | 4 |
Graft rejection | D006084 | — | — | — | 2 | — | 1 | — | 3 |
Immunosuppression therapy | D007165 | — | — | — | 1 | — | 1 | 1 | 3 |
Spondylarthritis | D025241 | — | — | — | — | — | 1 | 2 | 3 |
Transplantation | D014180 | — | — | 1 | — | — | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Systemic lupus erythematosus | D008180 | HP_0002725 | M32 | 2 | 7 | 1 | — | — | 7 |
Juvenile arthritis | D001171 | EFO_1002007 | M08 | — | — | 4 | — | 2 | 6 |
Lupus nephritis | D008181 | EFO_0005761 | — | 2 | 2 | 1 | — | — | 4 |
Myelodysplastic syndromes | D009190 | — | D46 | 1 | 2 | 1 | — | — | 3 |
Giant cell arteritis | D013700 | EFO_1001209 | M31.6 | — | 1 | 2 | — | — | 3 |
Sjogren's syndrome | D012859 | EFO_0000699 | M35.0 | — | 1 | 2 | — | — | 3 |
Granulomatosis with polyangiitis | D014890 | EFO_0005297 | M31.3 | 1 | 2 | 1 | — | — | 3 |
Anti-neutrophil cytoplasmic antibody-associated vasculitis | D056648 | — | I77.82 | — | 2 | 1 | — | — | 3 |
Neoplasms | D009369 | — | C80 | — | 1 | 1 | — | — | 2 |
Biphenotypic leukemia acute | D015456 | — | C95.0 | — | 1 | 1 | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 2 | 7 | — | — | 1 | 9 |
Graft vs host disease | D006086 | — | D89.81 | 4 | 7 | — | — | — | 8 |
Psoriasis | D011565 | EFO_0000676 | L40 | 2 | 2 | — | — | 1 | 5 |
Sickle cell anemia | D000755 | EFO_0000697 | D57 | 3 | 1 | — | — | — | 3 |
Interstitial lung diseases | D017563 | HP_0006530 | J84.89 | — | 3 | — | — | — | 3 |
Hypertension | D006973 | EFO_0000537 | I10 | — | 1 | — | — | 1 | 2 |
Asthma | D001249 | EFO_0000270 | J45 | — | 1 | — | — | 1 | 2 |
Heart transplantation | D016027 | EFO_0010673 | — | — | 2 | — | — | — | 2 |
Delayed graft function | D051799 | — | — | 1 | 1 | — | — | — | 2 |
Uveitis | D014605 | HP_0000554 | H20.9 | — | 2 | — | — | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 3 | — | — | — | — | 3 |
Renal insufficiency | D051437 | HP_0000083 | N19 | 1 | — | — | — | 1 | 2 |
Inflammation | D007249 | MP_0001845 | — | 1 | — | — | — | 1 | 2 |
Cardiovascular diseases | D002318 | HP_0001626 | — | 1 | — | — | — | 1 | 2 |
Mucopolysaccharidosis i | D008059 | — | E76.0 | 1 | — | — | — | — | 1 |
Aplastic anemia | D000741 | HP_0001915 | D61.9 | 1 | — | — | — | — | 1 |
Beta-thalassemia | D017086 | Orphanet_848 | D56.1 | 1 | — | — | — | — | 1 |
Wiskott-aldrich syndrome | D014923 | EFO_0003903 | D82.0 | 1 | — | — | — | — | 1 |
Hemophagocytic lymphohistiocytosis | D051359 | — | D76.1 | 1 | — | — | — | — | 1 |
Diamond-blackfan anemia | D029503 | EFO_0004130 | D61.01 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 1 | 1 |
Heart failure | D006333 | HP_0001635 | I50 | — | — | — | — | 1 | 1 |
Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | — | 1 | 1 |
Hemophilia a | D006467 | EFO_0007267 | D66 | — | — | — | — | 1 | 1 |
Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 1 | 1 |
Down syndrome | D004314 | EFO_0001064 | Q90 | — | — | — | — | 1 | 1 |
Pneumonia | D011014 | EFO_0003106 | — | — | — | — | — | 1 | 1 |
Mucocutaneous lymph node syndrome | D009080 | EFO_0004246 | M30.3 | — | — | — | — | 1 | 1 |
Hyperaldosteronism | D006929 | HP_0011736 | E26 | — | — | — | — | 1 | 1 |
Pulmonary arterial hypertension | D000081029 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Abatacept |
INN | abatacept |
Description | 1-25-oncostatin M (human precursor) fusion protein with CTLA-4 (antigen) (human) fusion protein with immunoglobulin G1 (human heavy chain fragment), bimolecular (146-146')-disulfide |
Classification | Protein |
Drug class | receptor molecules or membrane ligands, natural, modified or modified: T-cell receptors |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL1201823 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB01281 |
UNII ID | 7D0YB67S97 (ChemIDplus, GSRS) |