ARBEKACIN
Arbekacin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Duchenne muscular dystrophy | D020388 | EFO_0000429 | — | — | 1 | — | — | — | 1 |
| Muscular dystrophies | D009136 | HP_0003560 | G71.0 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Pneumonia | D011014 | EFO_0003106 | — | 1 | — | — | — | — | 1 |
| Bacterial pneumonia | D018410 | EFO_1001272 | J15.9 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | — | — | — | 1 | 1 |
| Communicable diseases | D003141 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ARBEKACIN |
| INN | arbekacin |
| Description | Arbekacin (INN) is a semisynthetic aminoglycoside antibiotic which was derived from kanamycin. It is primarily used for the treatment of infections caused by multi-resistant bacteria including methicillin-resistant Staphylococcus aureus (MRSA). Arbekacin was originally synthesized from dibekacin in 1973 by Hamao Umezawa and collaborators. It has been registered and marketed in Japan since 1990 under the trade name Habekacin. Arbekacin is no longer covered by patent and generic versions of the drug are also available under such trade names as Decontasin and Blubatosine.
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| Classification | Small molecule |
| Drug class | antibiotics obtained from Streptomyces kanamyceticus (related to kanamycin) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)CC[C@H]2N)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O |
Identifiers
| PDB | — |
| CAS-ID | 51025-85-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL426926 |
| ChEBI ID | 37922 |
| PubChem CID | 11398765 |
| DrugBank | DB06696 |
| UNII ID | G7V6SLI20L (ChemIDplus, GSRS) |
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Safety
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67 adverse events reported
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