Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | 2 | 4 | — | — | — | 6 |
Obstructive lung diseases | D008173 | — | — | 2 | 4 | — | — | — | 6 |
Lung diseases | D008171 | EFO_0003818 | J98.4 | — | 4 | — | — | — | 4 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 1 | — | — | — | 1 |
Insulin resistance | D007333 | EFO_0002614 | E88.819 | — | 1 | — | — | — | 1 |
Bronchiectasis | D001987 | — | J47 | — | 1 | — | — | — | 1 |
Fibrosis | D005355 | — | — | — | 1 | — | — | — | 1 |
Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
Pharmacokinetics | D010599 | — | — | 1 | — | — | — | — | 1 |
Pharmacological phenomena | D000069437 | — | — | 1 | — | — | — | — | 1 |
Drug common name | ALVELESTAT |
INN | alvelestat |
Description | Alvelestat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against neutrophil elastase. |
Classification | Small molecule |
Drug class | enzyme inhibitors: elastase inhibitors |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Cc1c(-c2ccnn2C)cc(C(=O)NCc2ccc(S(C)(=O)=O)cn2)c(=O)n1-c1cccc(C(F)(F)F)c1 |
PDB | — |
CAS-ID | 1240425-05-1 |
RxCUI | — |
ChEMBL ID | CHEMBL3617964 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | 6Y5629322X (ChemIDplus, GSRS) |