CEP-32496
Cep-32496 is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target RAF proto-oncogene serine/threonine-protein kinase and serine/threonine-protein kinase B-raf.
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Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
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YTD
1Y
2Y
5Y
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CEP-32496 |
| INN | agerafenib |
| Description | Cep-32496 is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target RAF proto-oncogene serine/threonine-protein kinase and serine/threonine-protein kinase B-raf. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C(F)(F)F)on4)c3)c2cc1OC |
Identifiers
| PDB | — |
| CAS-ID | 1188910-76-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2029988 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 78I4VEX88N (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
RAF1
RAF1
BRAF
BRAF
Organism
Homo sapiens
Gene name
RAF1
Gene synonyms
RAF
NCBI Gene ID
Protein name
RAF proto-oncogene serine/threonine-protein kinase
Protein synonyms
C-Raf proto-oncogene, serine/threonine kinase, cRaf, Oncogene RAF1, Proto-oncogene c-RAF, raf proto-oncogene serine/threonine protein kinase, Raf-1, v-raf-1 murine leukemia viral oncogene homolog 1, v-raf-1 murine leukemia viral oncogene-like protein 1
Uniprot ID
Mouse ortholog
Raf1 (110157)
RAF proto-oncogene serine/threonine-protein kinase (Q9QUU8)
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
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