AFIMETORAN
Afimetoran is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Commercial
No data
Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | 1 | 1 | — | — | — | 2 |
| Connective tissue diseases | D003240 | EFO_1001986 | M35 | — | 1 | — | — | — | 1 |
| Immune system diseases | D007154 | — | D89.9 | — | 1 | — | — | — | 1 |
| Autoimmune diseases | D001327 | EFO_0000540 | M30-M36 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 9 | — | — | — | — | 9 |
| Cutaneous lupus erythematosus | D008178 | EFO_0003834 | L93.1 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | AFIMETORAN |
| INN | afimetoran |
| Description | Afimetoran is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | toll-like receptor antagonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1c(-c2[nH]c3ccc(C4CCN(CC(N)=O)CC4)cc3c2C(C)C)cn2ncnc2c1C |
Identifiers
| PDB | — |
| CAS-ID | 2171019-55-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4650329 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | LXP7MZL0VF (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 25 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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