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Drug ReportsADRIFORANT
ADRIFORANT
Adriforant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target histamine H3 receptor and histamine H4 receptor.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Atopic dermatitisD003876EFO_0000274L2033
EczemaD004485HP_0000964L30.933
DermatitisD003872HP_0011123L30.933
PsoriasisD011565EFO_0000676L4011
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J4511
Healthy volunteers/patients11
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameADRIFORANT
INNadriforant
Description
Adriforant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target histamine H3 receptor and histamine H4 receptor.
Classification
Small molecule
Drug classhistamine H4 receptor antagonists
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Structure (InChI/SMILES or Protein Sequence)
CN[C@@H]1CCN(c2cc(NCC3CC3)nc(N)n2)C1
Identifiers
PDB
CAS-ID943057-12-3
RxCUI
ChEMBL IDCHEMBL1915540
ChEBI ID
PubChem CID
DrugBank
UNII IDD65H9YE9VU (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
HRH3
HRH3
HRH4
HRH4
Organism
Homo sapiens
Gene name
HRH3
Gene synonyms
GPCR97
NCBI Gene ID
Protein name
histamine H3 receptor
Protein synonyms
G protein-coupled receptor 97, G-protein coupled receptor 97, H3R
Uniprot ID
Mouse ortholog
Hrh3 (99296)
histamine H3 receptor (P58406)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 26 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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