ACUMAPIMOD
Acumapimod is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target mitogen-activated protein kinase 14.
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Variants
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Events Timeline
5D
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6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic obstructive pulmonary disease | D029424 | EFO_0000341 | J44.9 | — | 2 | — | — | — | 2 |
| Lung diseases | D008171 | HP_0002088 | J98.4 | — | 2 | — | — | — | 2 |
| Obstructive lung diseases | D008173 | HP_0006536 | — | — | 2 | — | — | — | 2 |
| Acute kidney injury | D058186 | HP_0001919 | N17 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ACUMAPIMOD |
| INN | acumapimod |
| Description | Acumapimod is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target mitogen-activated protein kinase 14. |
| Classification | Small molecule |
| Drug class | immunomodulators: mitogen-activated protein (MAP) kinase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 836683-15-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3545226 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 2F16KW647L (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
MAPK14
MAPK14
Organism
Homo sapiens
Gene name
MAPK14
Gene synonyms
CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
NCBI Gene ID
Protein name
mitogen-activated protein kinase 14
Protein synonyms
CSAID-binding protein, CSBP, cytokine suppressive anti-inflammatory drug binding protein, Cytokine suppressive anti-inflammatory drug-binding protein, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, p38 MAP kinase, p38 mitogen activated protein kinase, p38alpha Exip, SAPK2a, Stress-activated protein kinase 2a
Uniprot ID
Mouse ortholog
Mapk14 (26416)
mitogen-activated protein kinase 14 (P47811)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 31 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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