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Drug ReportsACETOHEXAMIDE
ACETOHEXAMIDE
Dymelor (acetohexamide) is a small molecule pharmaceutical. Acetohexamide was first approved as Dymelor on 1982-01-01. It is used to treat type 2 diabetes mellitus in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nutritional and metabolic diseasesD009750
endocrine system diseasesD004700
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Acetohexamide
Tradename
Company
Number
Date
Products
DYMELOREli LillyN-013378 DISCN1982-01-01
2 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
type 2 diabetes mellitusEFO_0001360D003924E11
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
— A10: Drugs used in diabetes
— A10B: Blood glucose lowering drugs, excl. insulins
— A10BB: Sulfonylureas for blood glucose lowering
— A10BB31: Acetohexamide
HCPCS
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Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 2 diabetes mellitusD003924EFO_0001360E11—1——45
Glucose intoleranceD018149HP_0000833R73.03—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cardiovascular diseasesD002318HP_0001626—————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameACETOHEXAMIDE
INNacetohexamide
Description
Acetohexamide is an N-sulfonylurea that is urea in which a hydrogen attached to one of the nitrogens is replaced by a p-acetylphenylsulfonyl group, while a hydrogen attached to the other nitrogen is replaced by a cyclohexyl group. It has a role as a hypoglycemic agent and an insulin secretagogue. It is a N-sulfonylurea and a member of acetophenones.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
CC(=O)c1ccc(S(=O)(=O)NC(=O)NC2CCCCC2)cc1
Identifiers
PDB—
CAS-ID968-81-0
RxCUI—
ChEMBL IDCHEMBL1589
ChEBI ID28052
PubChem CID1989
DrugBankDB00414
UNII IDQGC8W08I6I (ChemIDplus, GSRS)
Target
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Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5 adverse events reported
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