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SpringWorks Therapeutics
SpringWorks Therapeutics
(SWTX)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Ogsiveo
Nirogacestat
2023-11-27
2025-2043
Desmoid tumors
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
MIRDAMETINIB
healthy volunteers/patients
,
liver diseases
,
hepatic insufficiency
,
neurofibromatosis 1
,
neurofibromatoses
,
neurofibroma
,
neoplasms
,
plexiform neurofibroma
,
glioma
,
liposarcoma
,
myxoid liposarcoma
,
autonomic nervous system diseases
,
histiocytic sarcoma
Nirogacestat
healthy volunteers/patients
,
leukemia
,
neoplasms by histologic type
,
multiple myeloma
,
neoplasms
,
plasma cell neoplasms
,
breast neoplasms
,
triple negative breast neoplasms
,
pancreatic neoplasms
,
sarcoma
,
hiv infections
,
kaposi sarcoma
,
hematologic diseases
,
blood protein disorders
,
paraproteinemias
,
corneal diseases
,
ovarian neoplasms
,
granulosa cell tumor
,
fibroma
,
aggression
,
desmoid tumors
Benzimidazole
healthy volunteers/patients
,
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
plasma cell neoplasms
,
hematologic neoplasms
,
hodgkin disease
,
leukemia
,
neoplasms
,
lymphoma
,
non-hodgkin lymphoma
,
mantle-cell lymphoma
Tarenflurbil
healthy volunteers/patients
,
drug interactions
,
infections
,
hiv infections
,
acquired immunodeficiency syndrome
,
anemia
,
type 2 diabetes mellitus
Doconexent
melanoma
,
healthy volunteers/patients
,
prostatic neoplasms
,
renal cell carcinoma
,
breast neoplasms
,
ovarian neoplasms
,
pancreatic neoplasms
,
postmenopausal osteoporosis
,
head and neck neoplasms
,
colorectal neoplasms
,
neoplasms
,
non-hodgkin lymphoma
,
multiple myeloma
,
stomach neoplasms
,
adenocarcinoma
,
obesity
,
overweight
,
adenocarcinoma of lung
,
bronchiolo-alveolar adenocarcinoma
,
squamous cell carcinoma of head and neck
,
mantle-cell lymphoma
,
lung neoplasms
,
non-small-cell lung carcinoma
,
major depressive disorder
,
lymphoma
,
hodgkin disease
,
schizophrenia
,
osteoporosis
Terfenadine
allergic rhinitis seasonal
,
rhinitis
,
allergic rhinitis
,
pemphigus
,
allergic rhinitis perennial
Bevifimod
pharmacokinetics
,
inflammatory breast neoplasms
,
carcinoma
,
renal cell carcinoma
,
communicable diseases
,
pneumococcal infections
,
immune system diseases
,
triple negative breast neoplasms
,
diabetic foot
,
ulcer
,
foot ulcer
,
glioblastoma
,
gliosarcoma
,
astrocytoma
,
oligodendroglioma
,
small cell lung carcinoma
,
neoplasm metastasis
,
stomach neoplasms
,
esophageal neoplasms
,
hodgkin disease
,
adenocarcinoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
melanoma
,
bronchiolitis obliterans syndrome
,
meningitis
,
plasma cell neoplasms
,
squamous cell carcinoma of head and neck
,
ovarian epithelial carcinoma
,
human influenza
,
fallopian tube neoplasms
,
biliary tract neoplasms
,
prolymphocytic leukemia
,
pancreatic neoplasms
,
tuberculosis
,
hepatocellular carcinoma
,
liver neoplasms
,
head and neck neoplasms
,
pancreatic ductal carcinoma
,
induction chemotherapy
,
lung diseases
,
adenocarcinoma of lung
,
gestational diabetes
,
pregnancy in diabetics
,
coronary disease
,
large b-cell lymphoma diffuse
,
brain neoplasms
,
mucopolysaccharidoses
,
mucopolysaccharidosis i
,
follicular lymphoma
,
hematopoietic stem cell transplantation
,
peripheral arterial disease
,
atherosclerosis
,
intermittent claudication
,
peripheral vascular diseases
,
mumps
,
measles
,
chickenpox
,
rubella
,
meningococcal meningitis
,
haemophilus infections
,
cutaneous malignant melanoma
,
esophageal squamous cell carcinoma
,
urinary bladder neoplasms
,
diarrhea
,
rectal neoplasms
,
congenital abnormalities
,
megakaryoblastic leukemia acute
,
monocytic leukemia acute
,
myelomonocytic leukemia acute
,
erythroblastic leukemia acute
,
hypersensitivity
,
peanut hypersensitivity
,
squamous cell carcinoma
,
squamous cell neoplasms
,
prolymphocytic leukemia t-cell
,
allergic rhinitis
,
rhinitis
,
acquired immunodeficiency syndrome
,
sezary syndrome
,
mycosis fungoides
,
t-cell lymphoma cutaneous
,
pulmonary alveolar proteinosis
,
preleukemia
,
t-cell lymphoma peripheral
,
laryngeal neoplasms
,
emphysema
,
alpha 1-antitrypsin deficiency
,
breast neoplasms
,
colorectal neoplasms
,
multiple myeloma
,
non-small-cell lung carcinoma
,
leukemia
,
myeloid leukemia acute
,
b-cell chronic lymphocytic leukemia
,
lymphoma
,
recurrence
,
lung neoplasms
,
myelodysplastic syndromes
,
diphtheria
,
ovarian neoplasms
,
whooping cough
,
tetanus
,
graft vs host disease
,
meningococcal infections
,
poliomyelitis
,
healthy volunteers/patients
,
hiv infections
,
hematologic neoplasms
,
hemophilia b
,
pneumococcal pneumonia
,
hepatitis
,
haemophilus influenzae type b
,
infections
,
hepatitis b
,
myeloid leukemia
,
thrombosis
,
venous thrombosis
,
rheumatoid arthritis
,
ascites
,
bcr-abl positive chronic myelogenous leukemia
,
aplastic anemia
,
thrombotic thrombocytopenic purpura
,
insulinoma
,
neuroendocrine tumors
,
carcinoid tumor
,
vipoma
,
paraneoplastic syndromes
,
islet cell carcinoma
,
islet cell adenoma
,
gastrinoma
,
glucagonoma
,
somatostatinoma
,
pulmonary embolism
,
embolism
,
motor activity
,
st elevation myocardial infarction
,
glucose intolerance
,
hematologic diseases
,
inborn genetic diseases
,
blood coagulation disorders
,
x-linked genetic diseases
,
hemorrhagic disorders
,
inherited blood coagulation disorders
,
coagulation protein disorders
,
fetal growth retardation
,
thromboembolism
,
noonan syndrome
,
bacterial meningitis
,
tonsillitis
,
myeloproliferative disorders
,
chronic inflammatory demyelinating polyradiculoneuropathy
,
anemia
,
type 2 diabetes mellitus
,
type 1 diabetes mellitus
,
glycogen storage disease type ii
,
neoplasms
,
diabetes mellitus
,
prostatic neoplasms
,
non-hodgkin lymphoma
,
multiple sclerosis
,
hemophilia a
,
glycogen storage disease type iii
,
relapsing-remitting multiple sclerosis
,
covid-19
,
hyperglycemia
,
graft rejection
,
chronic kidney failure
,
insulin resistance
,
renal insufficiency
,
kidney transplantation
,
autologous transplantation
,
acute coronary syndrome
,
myocardial infarction
,
infarction
,
liver diseases
,
liver transplantation
,
psychology rejection
,
atrial fibrillation
,
pneumonia
,
hypertension
,
neutropenia
,
inflammation
,
heartburn
,
colitis
,
nasal polyps
,
asthma
,
inferior wall myocardial infarction
,
kidney diseases
,
coronary artery disease
,
immunosuppression therapy
,
fabry disease
,
anaphylaxis
,
glycogen storage disease
,
pregnancy
,
lymphoproliferative disorders
,
paraproteinemias
,
heart transplantation
,
reperfusion injury
LIFIRAFENIB
neoplasms
Nepidermin
neoplasms
,
triple negative breast neoplasms
,
squamous cell carcinoma of head and neck
,
carcinoma
,
colorectal neoplasms
,
breast neoplasms
,
pancreatic ductal carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
biliary tract neoplasms
,
esophageal squamous cell carcinoma
,
psoriasis
,
glioblastoma
,
non-small-cell lung carcinoma
,
hepatitis c
,
chronic hepatitis c
,
chronic hepatitis b
,
brain neoplasms
,
lymphoma
,
multiple myeloma
,
b-cell chronic lymphocytic leukemia
,
infections
,
communicable diseases
,
hepatitis
,
chronic hepatitis
,
hepatitis a
,
liver cirrhosis
,
parkinson disease
,
dyskinesias
,
gliosarcoma
,
ovarian neoplasms
,
leukemia
,
lymphoid leukemia
,
lung neoplasms
,
hidradenitis suppurativa
Endocrine
neoplasms
,
pheochromocytoma
,
adenocarcinoma
,
neuroendocrine tumors
,
anaplastic thyroid carcinoma
,
paraganglioma
,
endocrine gland neoplasms
,
carcinoma
,
invasive hydatidiform mole
,
circulating neoplastic cells
,
breast neoplasms
,
diabetes mellitus
,
lobular carcinoma
,
triple negative breast neoplasms
,
heart failure
,
coronary artery disease
,
ductal carcinoma breast
,
male breast neoplasms
Antineoplaston a10
chronic obstructive pulmonary disease
,
leukemia
,
myeloid leukemia acute
,
myeloid leukemia
,
rheumatoid arthritis
,
acne vulgaris
,
healthy volunteers/patients
,
neoplasms
,
non-hodgkin lymphoma
,
lymphoma
,
non-small-cell lung carcinoma
,
lung neoplasms
,
human influenza
,
arthralgia
,
premature birth
,
pneumococcal infections
,
streptococcal infections
,
papillomavirus infections
,
type 2 diabetes mellitus
,
diabetes mellitus
,
asthma
Gluconorm
sickle cell anemia
Pd0332991
healthy volunteers/patients
,
pancreatic neoplasms
,
lymphoma
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
castration-resistant prostatic neoplasms
,
endometrioid carcinoma
,
fallopian tube neoplasms
,
peritoneal neoplasms
,
melanoma
,
endometrial neoplasms
,
colorectal neoplasms
,
urinary bladder neoplasms
,
unknown primary neoplasms
,
pancreatic ductal carcinoma
,
liver failure
,
hepatic insufficiency
,
renal insufficiency
,
myelodysplastic syndromes
,
preleukemia
,
acute disease
,
non-small-cell lung carcinoma
,
lung neoplasms
,
carcinoma
,
triple negative breast neoplasms
,
multiple myeloma
,
head and neck neoplasms
,
ovarian neoplasms
,
non-hodgkin lymphoma
,
adenocarcinoma
,
leukemia
,
precursor cell lymphoblastic leukemia-lymphoma
,
mantle-cell lymphoma
,
sarcoma
,
renal cell carcinoma
,
squamous cell carcinoma
,
squamous cell neoplasms
,
lymphoid leukemia
,
ovarian epithelial carcinoma
,
kidney neoplasms
,
plasma cell neoplasms
,
colonic neoplasms
,
bone neoplasms
,
neuroblastoma
,
medulloblastoma
,
rhabdoid tumor
,
ewing sarcoma
,
rhabdomyosarcoma
,
diffuse intrinsic pontine glioma
,
small cell lung carcinoma
,
intraductal carcinoma noninfiltrating
,
b-cell lymphoma
,
prostatic neoplasms
,
brain neoplasms
,
glioma
,
oligodendroglioma
,
transitional cell carcinoma
,
myeloid leukemia acute
,
myeloid leukemia
,
hepatocellular carcinoma
,
liver neoplasms
,
glioblastoma
,
gliosarcoma
,
astrocytoma
,
liposarcoma
,
kidney diseases
,
urologic neoplasms
,
urogenital neoplasms
,
urologic diseases
,
neoplasms by site
,
glandular and epithelial neoplasms
,
neoplasms
,
squamous cell carcinoma of head and neck
,
neoplasm metastasis
,
male breast neoplasms
,
recurrence
,
unilateral breast neoplasms
,
breast neoplasms
,
radiotherapy
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