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SpringWorks Therapeutics
SpringWorks Therapeutics
(SWTX)
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Trade Name
Drug Name
Approved
Patent Expires
Indication
Ogsiveo
Nirogacestat
2023-11-27
2025-2043
Desmoid tumors
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
MIRDAMETINIB
neoplasms
,
astrocytoma
,
oligodendroglioma
,
ganglioneuroma
,
ganglioglioma
,
neuroepithelial neoplasms
,
neurocytoma
,
liposarcoma
,
myxoid liposarcoma
,
neurofibroma
,
glioma
,
central nervous system neoplasms
Nirogacestat
neoplasms
,
ovarian neoplasms
,
granulosa cell tumor
,
desmoid tumors
,
fibroma
,
aggression
LIFIRAFENIB
neoplasms
Nepidermin
postoperative nausea and vomiting
,
plasmacytoma
,
viral hepatitis human
,
psoriasis
,
neurologic manifestations
,
brain neoplasms
,
neoplasms
,
lymphoma
,
biliary tract neoplasms
,
glioma
,
follicular lymphoma
,
asthma
,
squamous cell neoplasms
,
large cell carcinoma
,
chronic obstructive pulmonary disease
,
lung diseases
,
cholangiocarcinoma
,
glioblastoma
,
mouth neoplasms
,
oropharyngeal neoplasms
,
laryngeal neoplasms
,
hypopharyngeal neoplasms
,
b-cell lymphoma marginal zone
,
mantle-cell lymphoma
,
endometrial neoplasms
,
transitional cell carcinoma
,
uterine cervical neoplasms
,
type 2 diabetes mellitus
,
diabetes mellitus
,
non-small-cell lung carcinoma
,
hepatitis c
,
hepatitis
,
hepatitis a
,
breast neoplasms
,
infections
,
communicable diseases
,
chronic hepatitis c
,
neoplasm metastasis
,
lung neoplasms
,
melanoma
,
vomiting
,
hiv infections
,
triple negative breast neoplasms
,
colorectal neoplasms
,
stomach neoplasms
,
esophageal neoplasms
,
nausea
,
head and neck neoplasms
,
ovarian neoplasms
,
osteoporosis
,
chronic hepatitis
,
dyslipidemias
,
adenocarcinoma
,
squamous cell carcinoma of head and neck
,
sleep initiation and maintenance disorders
,
clostridium infections
,
multiple myeloma
,
plasma cell neoplasms
,
squamous cell carcinoma
,
hodgkin disease
,
recurrence
,
ovarian epithelial carcinoma
,
migraine disorders
,
castration-resistant prostatic neoplasms
,
pancreatic neoplasms
,
hypertension
,
essential hypertension
,
nasopharyngeal neoplasms
,
acquired immunodeficiency syndrome
,
hiv
,
chronic renal insufficiency
,
kidney diseases
,
carcinoma
,
hepatocellular carcinoma
,
general anesthesia
,
neuromuscular blockade
,
intraabdominal infections
,
urinary tract infections
,
malignant mesothelioma
,
mesothelioma
,
postmenopausal osteoporosis
,
hypercholesterolemia
,
alzheimer disease
,
tuberculosis
,
erectile dysfunction
,
renal cell carcinoma
,
surgical wound infection
,
bacterial skin diseases
,
bacterial infections
,
staphylococcal infections
,
hiv-2
,
immunologic deficiency syndromes
,
urinary bladder neoplasms
,
diabetic foot
,
type 1 diabetes mellitus
,
cytomegalovirus infections
,
disease
,
glucose metabolism disorders
,
metabolic diseases
,
endocrine system diseases
,
allergic rhinitis
,
rhinitis
,
allergic rhinitis seasonal
,
liver neoplasms
,
fallopian tube neoplasms
,
pyelonephritis
,
pneumonia
,
bacterial pneumonia
,
heart failure
,
low back pain
,
back pain
,
liver failure
,
hepatic insufficiency
,
hepacivirus
,
prostatic hyperplasia
,
anesthesia
,
amnesia
,
cognitive dysfunction
,
obesity
,
overweight
,
prostatic neoplasms
,
plexiform neurofibroma
,
neurofibromatosis 1
,
hereditary breast and ovarian cancer syndrome
,
brca2 genes
,
central nervous system neoplasms
,
nervous system neoplasms
,
rheumatoid arthritis
,
arthritis
,
hip osteoarthritis
,
surgical blood loss
,
replacement arthroplasty hip
Endocrine
breast neoplasms
,
neoplasms
Pd0332991
healthy volunteers/patients
,
myelodysplastic syndromes
,
erbb-2 genes
,
syndrome
,
thromboembolism
,
drug therapy
,
inflammation
,
immunotherapy
,
myeloproliferative disorders
,
primary myelofibrosis
,
b-cell chronic lymphocytic leukemia
,
bcr-abl positive chronic myelogenous leukemia
,
myelomonocytic leukemia chronic
,
anemia
,
hodgkin disease
,
leukemia myeloid chronic atypical bcr-abl negative
,
myelodysplastic-myeloproliferative diseases
,
myeloid leukemia chronic-phase
,
myeloid leukemia accelerated phase
,
blast crisis
,
thrombocytosis
,
precursor b-cell lymphoblastic leukemia-lymphoma
,
erbb genes
,
endometrioid carcinoma
,
peritoneal neoplasms
,
hereditary breast and ovarian cancer syndrome
,
t-cell lymphoma
,
t-cell leukemia
,
ductal carcinoma breast
,
ductal carcinoma
,
invasive hydatidiform mole
,
postmenopause
,
unknown primary neoplasms
,
liver failure
,
hepatic insufficiency
,
meningioma
,
nervous system neoplasms
,
choroid plexus neoplasms
,
primitive neuroectodermal tumors
,
pinealoma
,
neuroepithelial neoplasms
,
neuroectodermal tumors
,
renal insufficiency
,
preleukemia
,
acute disease
,
adenocarcinoma of lung
,
retinoblastoma
,
cardiovascular diseases
,
myositis
,
thrombosis
,
immune system diseases
,
molecular targeted therapy
,
lung neoplasms
,
pancreatic neoplasms
,
non-small-cell lung carcinoma
,
melanoma
,
non-hodgkin lymphoma
,
precursor cell lymphoblastic leukemia-lymphoma
,
colorectal neoplasms
,
head and neck neoplasms
,
lymphoma
,
kidney neoplasms
,
prostatic neoplasms
,
multiple myeloma
,
adenocarcinoma
,
myeloid leukemia acute
,
glioma
,
colonic neoplasms
,
leukemia
,
ovarian epithelial carcinoma
,
medulloblastoma
,
glioblastoma
,
hepatocellular carcinoma
,
urinary bladder neoplasms
,
liver neoplasms
,
mantle-cell lymphoma
,
ewing sarcoma
,
liposarcoma
,
hematologic neoplasms
,
lymphoid leukemia
,
fallopian tube neoplasms
,
brain neoplasms
,
neuroblastoma
,
rhabdoid tumor
,
rhabdomyosarcoma
,
osteosarcoma
,
hereditary sensory and autonomic neuropathies
,
castration-resistant prostatic neoplasms
,
gastrointestinal neoplasms
,
esophageal neoplasms
,
uterine cervical neoplasms
,
rectal neoplasms
,
urologic neoplasms
,
urogenital neoplasms
,
central nervous system neoplasms
,
ependymoma
,
primitive neuroectodermal tumors peripheral
,
hepatoblastoma
,
wilms tumor
,
langerhans-cell histiocytosis
,
myeloid leukemia
,
chordoma
,
oligodendroglioma
,
pancreatic ductal carcinoma
,
gliosarcoma
,
astrocytoma
,
digestive system neoplasms
,
esophageal squamous cell carcinoma
,
stomach neoplasms
,
uterine neoplasms
,
skin neoplasms
,
plasma cell neoplasms
,
bone neoplasms
,
gastrointestinal stromal tumors
,
diffuse intrinsic pontine glioma
,
histiocytic sarcoma
,
juvenile xanthogranuloma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
small cell lung carcinoma
,
intraductal carcinoma noninfiltrating
,
b-cell lymphoma
,
thymus neoplasms
,
neuroendocrine tumors
,
neuroendocrine carcinoma
,
islet cell carcinoma
,
lobular carcinoma
,
transitional cell carcinoma
,
t-cell lymphoma peripheral
,
germ cell and embryonal neoplasms
,
teratoma
,
testicular neoplasms
,
seminoma
,
germinoma
,
dermoid cyst
,
residual neoplasm
,
covid-19
,
thromboinflammation
,
hormone replacement therapy
,
kidney diseases
,
urologic diseases
,
glandular and epithelial neoplasms
,
salivary gland neoplasms
,
therapeutics
,
myxoid liposarcoma
,
high-throughput nucleotide sequencing
,
neoplasms
,
neoplasm metastasis
,
triple negative breast neoplasms
,
sarcoma
,
male breast neoplasms
,
squamous cell carcinoma of head and neck
,
squamous cell carcinoma
,
recurrence
,
breast diseases
,
squamous cell neoplasms
,
neoplasms by site
,
skin diseases
,
unilateral breast neoplasms
,
neoadjuvant therapy
,
von hippel-lindau disease
,
breast neoplasms
,
carcinoma
,
ovarian neoplasms
,
renal cell carcinoma
,
endometrial neoplasms
,
thyroid neoplasms
,
therapeutic equivalency
,
radiotherapy
,
neutropenia
,
bone diseases
,
venous thromboembolism
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